研究成果列表
單位名稱生化科技學系教師姓名陳瑞傑
教師分級副教授專兼任專任
在校狀態在職行政職務生物安全會委員

期刊論文(共計36筆)
序號學年度學期年度月份作者題目通訊作者作者順位期刊名稱卷數頁數關鍵字
1092220043Su CC, Chiu HH, Chang CC, Chen JC, Hsu SMCD30 is involved in inhibition of T-cell proliferation by Hodgkins Reed-Sternberg cells其他Cancer research64 2148-52  
2099220115Chen JC, Chuang JG, Su YY, Chiang BL, Lin YS, Chow LPThe protease allergen Pen c 13 induces allergic airway inflammation and changes in epithelial barrier integrity and function in a murine model第一順位The Journal of biological chemistry286 26667-79  
31011201212Chen JC, Chang YW, Hong CC, Yu YH, Su JLThe Role of the VEGF-C/VEGFRs Axis in Tumor Progression and Therapy第一順位International journal of molecular sciences14 88-107  
4100220124Chen JC, Chiu LL, Lee KL, Huang WN, Chuang JG, Liao HK, Chow LPIdentification of critical amino acids in an immunodominant IgE epitope of Pen c 13, a major allergen from Penicillium citrinum第一順位PloS onee34627  
51021201312Chen JC, Fong YC, Tang CHNovel strategies for the treatment of chondrosarcomas: targeting integrins第一順位BioMed research international2013 396839  
61031201411Chen JC, Yang ST, Lin CY, Hsu CJ, Tsai CH, Su JL, Tang CH*BMP-7 enhances cell migration and αvβ3 integrin expression via a c-Src-dependent pathway in human chondrosarcoma cells第一順位PloS onee112636  
71031201411Liu GT, Chen HT, Tsou HK, Tan TW, Fong YC, Chen PC, Yang WH, Wang SW, Chen JC, Tang CHCCL5 promotes VEGF-dependent angiogenesis by down-regulating miR-200b through PI3K/Akt signaling pathway in human chondrosarcoma cells其他Oncotarget10718  
81031201411Huang HC, Tao MH, Hung TM, Chen JC, Lin ZJ, Huang C(-)-Epigallocatechin-3-gallate inhibits entry of hepatitis B virus into hepatocytes其他Antiviral research111 100  
91031201412Yang WH, Chen JC, Hsu KH, Lin CY, Wang SW, Wang SJ, Chang YS, Tang CHLeptin increases VEGF expression and enhances angiogenesis in human chondrosarcoma cells第二順位Biochimica et biophysica acta1840 3483  
101031201412Chen JC, Su YH, Chiu CF, Chang YW, Yu YH, Tseng CF, Chen HA, Su JLSuppression of Dicer increases sensitivity to gefitinib in human lung cancer cells第一順位Annals of surgical oncology21 S555-63  
11102220143Chen HT, Tsou HK, Chen JC, Shih JM, Chen YJ, Tang CHAdiponectin enhances intercellular adhesion molecule-1 expression and promotes monocyte adhesion in human synovial fibroblasts第三順位PloS onee92741  
12103220155Chen JC, Chen YJ, Lin CY, Fong YC, Hsu CJ, Tsai CH, Su JL, Tang CHAmphiregulin enhances alpha6beta1 integrin expression and cell motility in human chondrosarcoma cells through Ras/Raf/MEK/ERK/AP-1 pathway第一順位Oncotarget11434-46  
13103220156CC Yeh, ZF Wu, JC Chen, CS Wong, CJ Huang, JS Wang, CC Chien.Association between extracellular signal-regulated kinase expression and the anti-allodynic effect in rats with spared nerve injury by applying immediate pulsed radiofrequency第三順位BMC anesthesiology15 1-8  
141051201611Lee IN, Lu YP, Chen JC, Yang CH, Huang JW, Yang JT, Chiou PY, and Lin MYEmerging Physical Approaches for Promoting siRNA Intracellular Delivery for Cancer Therapy第三順位Current Organic Chemistry20 2961-2971  
15105120169Chen JC, Hsieh MJ, Chen CJ, Lin JT, Lo YS, Chuang YC, Chien SY, Chen MKPolyphyllin G induce apoptosis and autophagy in human nasopharyngeal cancer cells by modulation of AKT and mitogen-activated protein kinase pathways in vitro and in vivo第一順位Oncotarget70276  
16105120171Hsieh MJ, Chen JC, Yang WE, Chien SY, Chen MK, Lo YS, Hsi YT, Chuang YC, Lin CC, Yang SFDehydroandrographolide inhibits oral cancer cell migration and invasion through NF-κB-, AP-1-, and SP-1-modulated matrix metalloproteinase-2 inhibition第二順位Biochemical Pharmacology130 10-20  
171061201711Chen JC, Hsieh MC, Lin SH, Lin CC, Hsi YT, Lo YS, Chuang YC, Hsieh MJ, Chen MKCoronarin D induces reactive oxygen species-mediated cell death in human nasopharyngeal cancer cells through inhibition of p38 MAPK and activation of JNK.第一順位Oncotarget.108006-108019  
18105220173Hsieh MJ, Lin CW, Chen MK, Chien SY, Lo YS, Chuang YC, Hsi YT, Lin CC, Chen JC, Yang SFInhibition of cathepsin S confers sensitivity to methyl protodioscin in oral cancer cells via activation of p38 MAPK/JNK signaling pathways其他Scientific Reports45039  
191071201812Chen JC, Huang C, Lee IN, Wu YP, Tang CH.Amphiregulin enhances cell migration and resistance to doxorubicin in chondrosarcoma cells through the MAPK pathway.第一順位Molecular Carcinogenesis57 1816-1824  
20107120189Lai YH, Sun CP, Huang HC, Chen JC, Liu HK, Huang CEpigallocatechin gallate inhibits hepatitis B virus infection in human liver chimeric mice其他BMC Complement Altern Med. 248-254  
21108120198Chen JC, Lee IN, Huang C, Wu YP, Chung CY, Lee MH, Lin MH, Yang JTValproic acid-induced amphiregulin secretion confers resistance to temozolomide treatment in human glioma cells.第一順位BMC cancer19 756  
22108120199Hsieh MJ, Chen YH, Lee IN, Huang C, Ku YJ, and Chen JCSecreted amphiregulin promotes vincristine resistance in oral squamous cell carcinoma其他International journal of oncology55 949-959  
23108120201Hsieh MJ, Huang C, Lin CC, Tang CH, Lin CY, Lee IN, Huang HC, Chen JC.Basic fibroblast growth factor promotes doxorubicin resistance in chondrosarcoma cells by affecting XRCC5 expression其他Molecular carcinogenesisdoi: 10.1002/mc.23153.  
241091202010Lee IN, Yang JT, Hsieh MI, HuangC, Huang HC, Ku YJ, Wu YP, Huang KC, Chen JC Knockdown of Amphiregulin Triggers Doxorubicin-Induced Autophagic and Apoptotic Death by Regulating Endoplasmic Reticulum Stress in Glioblastoma Cells其他Journal of molecular neuroscience : MN.70 1461-1470  
25108220203Huang C, Lu HF, Chen YH, Chen JC, Chou WH, Huang HC.Curcumin, demethoxycurcumin, and bisdemethoxycurcumin induced caspase-dependent and -independent apoptosis via Smad or Akt signaling pathways in HOS cells.其他BMC complementary medicine and therapies20 68  
26108220205Chiang H, Lu HF, Chen JC, Chen YH, Sun HT, Huang HC, Tien HH, and Huang CAdlay Seed (Coix lacryma-jobi L.) Extracts Exhibit a Prophylactic Effect on Diet-Induced Metabolic Dysfunction and Nonalcoholic Fatty Liver Disease in Mice第三順位Evidence-Based Complementary and Alternative Medicine9519625 9519625  
27109120211Chiou WC, Chen JC, Chen YT, Yang JM, Hwang LH, Lyu YS, Yang HY, Huang CThe inhibitory effects of PGG and EGCG against the SARS-CoV-2 3C-like protease第一順位Biochemical and biophysical research communications32299-3  
281101202111Lin FY, Huang KF, Chen JC, Lai MF, Ma KH, Yeh CCThe Clinical Application of Pulsed Radiofrequency Induces Inflammatory Pain via MAPKs Activation: A Novel Hint for Pulsed Radiofrequency Treatment第一順位International journal of molecular sciences1-19  
291101202111Huang H, Huang HC, Chiou WC, Lin LC, Chen JC, Liu HK, Lai YH, Huang CErgosterol peroxide inhibits HBV infection by inhibiting the binding of the pre-S1 domain of LHBsAg to NTCP其他Antiviral research195 1-10  
301101202112Huang C, Lin ZJ, Lee CJ, Lai WH, Chen JC, Huang HCε-Viniferin and α-viniferin alone or in combination induced apoptosis and necrosis in osteosarcoma and non-small cell lung cancer cells其他Food and chemical toxicology158 1-15  
31109220214Lee IN, Tsung JT, Huang C, Huang HC, Wu YP, Chen JCElevated XRCC5 expression level can promote temozolomide resistance and predict poor prognosis in glioblastoma其他Oncology Letters21 443  
32110120221Yang KS, Che PC, Hsieh MJ, Lee IN, Wu YP, Chen MS, Chen JCPropofol induces apoptosis and ameliorates 5‑fluorouracil resistance in OSCC cells by reducing the expression and secretion of amphiregulin其他Molecular medicine reports1-11  
33111120231Chen JC, Shih HC, Lin CY, Guo JH, Huang C, Huang HC, Chong ZY, Tang CH.MicroRNA-631 Resensitizes Doxorubicin-Resistant Chondrosarcoma Cells by Targeting Apelin第一順位International Journal of Molecular Sciences24 839  
34111220234Yang JT, Lee IN, Huang C, Huang HC, Wu YP, Chong ZY, Chen JCADAM17 confers temozolomide resistance in human glioblastoma cells and miR-145 regulates its expression其他International Journal of Molecular Sciences24 7703  
351122202404Chen MS, Chong ZY, Huang C, Huang HC, Su PH, Chen JC.Lidocaine attenuates TMZ resistance and inhibits cell migration by modulating the MET pathway in glioblastoma cells其他Oncology Reports1-14  
36112220242Chen MS, Hu CL, Jiang SK, Chong ZY, Chen JC.Modulation of secretory factors by lipofundin contributes to its anti‑neuroinflammatory effects其他EXPERIMENTAL AND THERAPEUTIC MEDICINE27 1-5  

會議論文(共計15筆)
序號學年度學期年度月份作者題目通訊作者作者順位發表性質會議論文集或研討會名稱地點
1099120109Chow LP, Chen JCIntegration of proteomics and bioinformatics tools to analyze the differential lung proteome in a mouse model of Pen c 13 allergen-induced allergic airway inflammation第二順位壁報發表 Human proteome organisation 2010 world congress  
2103220153Wu YP, Tang CH and Chen JC Suppression of amphiregulin increases sensitivity to doxorubicin in human chondrosarcoma cells其他壁報發表 The 30th Joint Annual Conference of Biomedical Science National Defense Medical Center, Taipei, Taiwan 
3103220153Huang KC, Lee IN and Chen JC Amphiregulin promotes enhanced resistance to doxorubicin in glioblastoma multiforme by regulating autophagy其他壁報發表 The 30th Joint Annual Conference of Biomedical Science National Defense Medical Center, Taipei, Taiwan 
41051201611Huang CW, Yang SF, Hsieh MJ, and Chen JCCathepsin S is involved in natural compound methyl protodioscin-induced cell death in oral cancer其他壁報發表 The 6th International Symposium in Phytochemicals-Bioactivities and Disease Prevention of Phytochemi  
51051201611Chan SP, Yang SF, Hsieh MJ, and Chen JCNatural compound methyl protodioscin induces apoptosis and G2/M phase cell cycle arrest in oral cancer cells其他壁報發表 The 6th International Symposium in Phytochemicals-Bioactivities and Disease Prevention of Phytochemi  
61051201611Chen HT, Yang SF, Hsieh MJ, and Chen JCNatural compound methy protodioscin induces autophagy in oral cancer cells其他壁報發表 The 6th International Symposium in Phytochemicals-Bioactivities and Disease Prevention of Phytochemi  
7104220163Wu YP, Tseng SM, Chen JCThe use of antibody array to identify a promising new therapeutic target for amphiregulin signaling in the migration activity of human chondrosarcoma cells其他壁報發表 The 31th Joint Annual Conference of Biomedical Science  
8105220173陳頌邦、陳慧婷、黃芹濰、陳瑞傑Upregulation of secreted amphiregulin induces Vincristine Sulfate (VCR) resistance in oral cancer cells其他壁報發表 第三十二屆生醫年會  
9106220183鄭庭茜、吳芷吟、宋政穎、陳瑞傑Secreted amphiregulin promotes vincristine resistance in oral squamous cell carcinoma其他壁報發表 第三十三屆生醫年會  
10107220193陳立洲、陳瑞傑Basic fibroblast growth factor modulates the levels of XRCC5 to enhance doxorubicin resistance in chondrosarcoma其他壁報發表 第三十四屆生醫年會  
11110220223蘇品瑄,陳瑞傑Screening of the Extracts from Traditional Chinese Medicine with Neuroprotective and Anti-inflammatory Effects其他壁報發表 第36屆生物醫學聯合學術年會(JACBS)  
12111220233江柔葳,張智泳,黃心妤,陳瑞傑Lidocaine can inhibit Glioblastoma Multiforme其他壁報發表 第37屆生物醫學聯合學術年會(JACBS)  
13111220233Yan-Min Chen , Zhi-Yong Chong , Hsin-Yu Haung , Yan Tang Huang , Jui-Chieh Chen Lidocaine Enhances TMZ Sensitivity in Glioblastoma Multiforme 其他壁報發表 第37屆生物醫學聯合學術年會(JACBS)  
14111220235張智泳, 陳瑞傑New Directions for Treating GBM with Lidocaine: A Comprehensive Exploration其他壁報發表 Merck Young Scientist Award 默克年輕科學人獎2023  
15112120238黃心妤,陳明山,姜信匡,江柔葳,陳燕旻,陳瑞傑Characterizing the gut microbiota composition in Taiwanese hypertensive patients using 16S rRNA sequencing analysis其他壁報發表 第27屆細菌學研討會  

研究計畫(共計12筆)
備註欄說明:「教師研究計畫管理系統轉入之計畫」(係指依「國立嘉義大學產學合作計畫實施要點」第3點規定,與政府機關、法人、公民營事業機構、民間團體、學術研究機構等合作辦理有關事項,以本校名義與合作機構辦理簽約,其經費撥入本校之產學合作計畫。)
序號學年度學期年度月份參與性質委辦單位計畫名稱開始日期結束日期經費備註欄
11031201410計畫主持人國家科學及技術委員會探討雙調蛋白在骨癌轉移中之功能與機轉2014/10/012015/07/31500000
21041201508計畫主持人國家科學及技術委員會探討雙調蛋白在阿黴素治療軟骨肉瘤敏感性之角色2015/08/012016/07/31754000
31042201607計畫主持人國家科學及技術委員會大專生計畫-木黴菌乙醯轉移酵素純化及基因選殖(連冠智)2016/07/012017/02/2848000
41042201607計畫主持人國家科學及技術委員會Using proteomics to identify key secreted proteins associated with metastasis in chondrosarcoma.2016/07/012017/02/280
51051201608計畫主持人國家科學及技術委員會探討雙調蛋白在阿黴素治療軟骨肉瘤敏感性之角色 (II)2016/08/012017/07/311102000
61051201608共同主持人國家科學及技術委員會以大鼠中大腦動脈阻塞模式探討脫水作用對缺血性中風損傷惡化之影響2016/08/012017/07/31900000
71071201808計畫主持人國家科學及技術委員會鑑定在人類口腔癌細胞中與長春新鹼抗性相關的關鍵性分泌蛋白2018/08/012019/07/31810000
81072201907計畫主持人國家科學及技術委員會大專生計畫:探討調控成纖維細胞生長因子的微小核醣核酸對人類軟骨肉瘤之阿黴素抗藥性的影響:(指導學生:陳立洲)2019/07/012020/02/2848000教師研究計畫管理系統轉入之計畫
91082202007計畫主持人國家科學及技術委員會探討調控去整合素和金屬蛋白酶17(ADAM17)的微型核醣核酸對膠質母細胞瘤之替莫唑胺抗藥性的影響2020/07/012021/02/280
101082202007計畫主持人國家科學及技術委員會探討調控Apelin的微小核醣核酸對人類軟骨肉瘤之阿黴素抗藥性的影響2020/07/012021/02/280
111112202307計畫主持人國家科學及技術委員會大專學生研究計畫大專生計畫:探討Galectin-1在膠質母細胞瘤中對替莫唑胺抗性的影響2023/07/012024/02/2848000教師研究計畫管理系統轉入之計畫
121112202307計畫主持人國家科學及技術委員會大專學生研究計畫大專生計畫:探討Galectin-1在膠質母細胞瘤中對替莫唑胺抗性的影響-指導學生:江柔葳2023/07/012024/02/2948000教師研究計畫管理系統轉入之計畫

獲獎榮譽(共計6筆)
序號學年度學期年度月份獲獎種類獲獎名稱頒獎單位
1103220155本校104學年度研究生論文海報宣讀競賽優選本校
2103220155本校104學年度研究生論文海報宣讀競賽佳作本校
31051201611國際性2016年國際研討會壁報比賽第三名本校
4104220166本校105年度學生學術研究成果優良海報選第一名本校
5106220185本校106學年度研究生論文海報宣讀競賽優選本校
6106220185本校107年度學生學術研究成果優良海報選第一名本校

學術活動(共計46筆)
序號學年度學期年度月份活動分類活動名稱活動地點/期刊學報/比賽名稱
11041201508學術期刊論文審查擔任審查委員oncotarget 
2103220153出席國際研討會第三十屆生物醫學聯合學術年會國防醫學院 
31042201605學術期刊論文審查擔任審查委員oncotarget 
41042201606學術期刊論文審查擔任審查委員oncotarget 
51042201607學術期刊論文審查擔任審查委員oncotarget 
61051201610學術期刊論文審查擔任審查委員oncotarget 
71051201611出席國際研討會2016第六屆 國際植物化合物暨疾病預防與功能評估研討會嘉義大學 
81051201611學術期刊論文審查擔任審查委員oncotarget 
91051201612學術期刊論文審查擔任審查委員oncotarget 
10104220163出席國際研討會第31屆生物醫學聯合學術年會國防醫學院 
111052201703學術期刊論文審查擔任審查委員oncotarget 
121061201708學術期刊論文審查擔任審查委員oncotarget 
131061201708學術期刊論文審查擔任審查委員oncotarget 
14105220173出席研討會第三十二屆生物醫學聯合學術年會國防醫學院 
15105220173出席國際研討會台大雲林分院13周年慶國際學術研討會-肝癌及病毒性肝炎治療新視野國立雲林科技大學國際會議廳 
161062201804學術期刊論文審查擔任審查委員oncotarget 
171071201809學術期刊論文審查擔任論文審查aging 
181071201810學術期刊論文審查擔任論文審查BMC cancer 
191071201811學術期刊論文審查擔任論文審查aging 
201072201905學術期刊論文審查期刊論文審查BMC cancer 
211072201906學術期刊論文審查擔任論文審查aging 
221072201907學術期刊論文審查期刊論文審查aging 
231081201908學術期刊論文審查期刊論文審查BMC cancer 
241081201909學術期刊論文審查期刊論文審查aging 
251081201912學術期刊論文審查期刊論文審查BMC cancer 
261081202001學術期刊論文審查期刊論文審查BMC cancer 
27108220204出席國際研討會台灣生物科技暨健康產業協會永續發展與綠色科技研討會南華大學 
281101202108學術期刊論文審查擔任審查委員cancers 
291101202108學術期刊論文審查 擔任審查委員World Journal of Surgical Oncology 
301101202109學術期刊論文審查擔任審查委員molecules 
311101202110學術期刊論文審查期刊論文審查Bioengineered 
321101202111學術期刊論文審查期刊論文審查Bioengineered 
331102202205學術期刊論文審查擔任審查委員JCM 
341102202206學術期刊論文審查擔任審查委員Molecular Biology Reports 
351102202207學術期刊論文審查擔任審查委員Bioengineering 
361111202210學術期刊論文審查擔任審查委員cancers 
371111202210學術期刊論文審查期刊論文審查Bioengineered 
381111202211學術期刊論文審查擔任審查委員Bioengineered 
391111202301學術期刊論文審查擔任審查委員British Journal of Cancer 
401111202301學術期刊論文審查擔任審查委員IJMS 
411112202302學術期刊論文審查擔任審查委員JFB 
421112202304學術期刊論文審查擔任審查委員IJMS 
431112202305學術期刊論文審查擔任審查委員Journal of Translational Medicine 
441112202305學術期刊論文審查期刊論文審查Antioxidants 
451112202307學術期刊論文審查期刊論文審查Aging 
461121202312學術期刊論文審查擔任審查委員Immuno 

推廣工作(共計22筆)
序號學年度學期年度月份推廣類別推廣名稱推廣地點
11032201504學術演講或教學講習主講擔任 基因的奧秘之演講者嘉義高中 
21042201607輔導中國醫藥大學基礎醫學研究所楊東盈碩士班論文口試中國醫藥大學 
31042201607輔導中國醫藥大學基礎醫學研究所黃鈺文口試委員 
41042201607輔導中國醫藥大學基礎醫學研究所鄭宇哲口試委員中國醫藥大學 
51042201607輔導中國醫藥大學基礎醫學研究所黃雅欣口試委員中國醫藥大學 
61051201610學術演講或教學講習主講擔任 科學發展與疾病的關係之演講者嘉義高中 
71051201611學術演講或教學講習主講擔任 從科學看疾病治療之演講者中國醫藥大學北港分部 
81052201705學術演講或教學講習主講106年度學生學術研究成果優良海報評選競賽評審委員生命科學院 
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