期刊論文(共計18筆) |
序號 | 學年度 | 學期 | 年度 | 月份 | 作者 | 題目 | 通訊作者 | 作者順位 | 期刊名稱 | 卷數 | 頁數 | 關鍵字 |
1 | 098 | 1 | 2010 | 1 | Jiann-Jyh Huang et al. | Synthesis of 2-Aryl-2H-(1,2,4)triazoloquinolin-3-one and 2-Aryl-2H-(1,2,4)- triazoloisoquinolin-3-one Derivatives from a-Chloroformylaryl-hydrazines Hydrochloride | 否 | 第一順位 | Tetrahedron | 66 | 930–934 | |
2 | 099 | 1 | 2010 | 12 | Jiann-Jyh Huang* et al. | Synthesis and Structure–Activity Relationship of 3-O-Acylated (–)-Epigallocatechins as 5a-Reductase Inhibitors | 是 | 其他 | European Journal of Medicinal Chemistry | 45 | 6068–6076 | |
3 | 098 | 2 | 2010 | 6 | Jiann-Jyh Huang* et al. | One-pot Ethynylation and Catalytic Desilylation in Synthesis of Mestranol and Levonorgestrel | 是 | 其他 | Tetrahedron | 66 | 4068-4072 | |
4 | 099 | 1 | 2010 | 8 | Jiann-Jyh Huang* et al. | Discovery of Pyrrole–Indoline-2-ones as Aurora Kinase Inhibitors with Different Inhibition Profile | 是 | 第一順位 | Journal of Medicinal Chemistry | 53 | 5929–5941 | |
5 | 101 | 1 | 2012 | 10 | Jiann-Jyh Huang* et al. | Synthesis and Antiproliferative Activities of Ottelione A Analogues | 是 | 其他 | ACS Medicinal Chemistry Letters | 3 | 1075–1080 | |
6 | 102 | 1 | 2014 | 1 | Huang, L. Y. L.; Lee, Y.-S.; Huang, J.-J. et al. | Characterization of the biological activity of a potent small molecule Hec1 inhibitor TAI-1 | 否 | 其他 | Journal of Experimental and Clinical Research | 33 | 6 | |
7 | 103 | 1 | 2014 | 11 | Jiann-Jyh Huang* et al. | Design and synthesis of pyrrole–5-(2,6-dichlorobenzyl)sulfonylindolin-2-ones with a C-3‘ side chains as potent Met kinase inhibitors | 是 | 其他 | RSC Advances | 4 | 58990–58998 | Met, c-Met, indolin-2-one, kinase, oncology, hepatocyte growth factor, scatter factor |
8 | 102 | 2 | 2014 | 3 | Jiann-Jyh Huang* et al. | One-flask synthesis of 1,3,5-trisubstituted 1,2,4-triazoles from nitriles and hydrazonoyl chlorides via 1,3-dipolar cycloaddition | 是 | 其他 | RSC Advances | 4 | 14215-14220 | |
9 | 102 | 2 | 2014 | 5 | Jiann-Jyh Huang* et al. | Discovery of 4-Aryl-N-arylcarbonyl-2-aminothiazoles as Hec1/Nek2 inhibitors. Part I: optimization of in vitro potencies and pharmacokinetic properties | 是 | 其他 | Journal of Medicinal Chemistry | 57 | 4098-4110 | |
10 | 102 | 2 | 2014 | 5 | Wang, L.-Y.; Chang, E.-C.; Yeh, M.-Y.; Chung, Y. H.; Huang, J.-J.; Wong, F. F. | Synthesis of 1,3,4-oxadiazole-based aromatic and heterocyclic/phenylpyrazole derivatives | 否 | 其他 | Heteroatom Chemistry | 25 | 171-177 | |
11 | 103 | 1 | 2014 | 9 | 31. Huang, L. Y. L.; Chang, C.-C.; Lee, Y.-S.; Huang, J. J.; Chuang, S.-H.; Chang, J.-M.; Kao, K.-J. | Inhibition of Hec1 as a novel approach for treatment of primary liver cancer | 否 | 其他 | Cancer Chemother. Pharmacol. | 74 | 511-520 | |
12 | 103 | 1 | 2014 | 9 | Huang, L. Y. L.; Chang, C.-C.; Lee, Y.-S.; Chang, J.-M.; Huang, J.-J.; Chuang, S.-H.; Kao, K.-J.; La | Activity of a novel Hec1-targeted anticancer compound against breast cancer cell lines in vitro and in vivo | 否 | 其他 | Molecular Cancer Therapeutics | 13 | 1419-1430 | |
13 | 103 | 2 | 2015 | 4 | 黃建智 | Vilsmeier–Haack reagent-promoted formyloxylation of a-chloro-N-arylacetamides by
formamide | 否 | 第一順位 | RSC Advances | 5 | 35934-35939 | ilsmeier–Haack reagent, formyloxylation, formate ester, formamide, phosphorous bromide, α-formyloxy-N-arylacetamide |
14 | 108 | 2 | 2020 | 3 | Jiann-Jyh Huang et. al. | The inhibition profiles of 4′-acylpyrrole–5-fluoroindolin-2-ones with a C-3′ side chain for VEGFR2, PDGFR-β, and FGFR-1 protein kinases | 是 | 第一順位 | Journal of the Chinese Chemical Society | 67 | 422-429 | Pyrrole–indoline-2-one;, VEGFR2, ; PDGFR-β, ; FGFR-1, ; kinaseKinase, ; inhibition Inhibition profile |
15 | 108 | 2 | 2020 | 4 | Shih-Hsien Chuang..//...Jiann-Jyh Huang* | Discovery of T-1101 tosylate as a first-in-class clinical candidate for Hec1/Nek2 inhibition in cancer therapy | 是 | 其他 | European Journal of Medicinal Chemistry | 191 | 112118 | |
16 | 109 | 2 | 2021 | 2 | Hsueh, W.-Y./.../Huang, J.-J.* | Copper(I)-catalyzed nitrile-addition/N-arylation ring-closure cascade: synthesis of 5,11-dihydro-6H-indolo(3,2-c)quinolin-6-ones as potent topoisomerase-I inhibitors | 是 | 其他 | Journal of Medicinal Chemistry | 64 | 1435-1453 | |
17 | 109 | 2 | 2021 | 2 | Lee, C.-I./.../Huang, J.-J.* | Design and synthesis of 4-anilinoquinazolines as Raf kinase inhibitors. Part 1. Selective B-Raf/B-RafV600E and potent EGFR/VEGFR2 inhibitory 4-(3-hydroxyanilino)-6-(1H-1,2,3-triazol-4-yl)quinazolines | 是 | 其他 | Bioorganic Chemistry | 109 | 104715 | |
18 | 110 | 1 | 2021 | 9 | Pei-Yi Tsai /.../ Jiann-Jyh Huang* | Design, synthesis, and in vitro/vivo anticancer activity of 4-substituted 7-(3-fluoro-4-methoxybenzyl)-7H-pyrrolo(2,3-d)pyrimidines | 是 | 其他 | Journal of the Chinese Chemical Society | 68 | 1761-1770 | |
會議論文(共計13筆) |
序號 | 學年度 | 學期 | 年度 | 月份 | 作者 | 題目 | 通訊作者 | 作者順位 | 發表性質 | 會議論文集或研討會名稱 | 地點 |
1 | 096 | 1 | 2007 | 11 | Huang, J.-J. et. al | Development of Novel Quinolinone Derivatives as Topoisomerase I Inhibitors | 是 | 第一順位 | 書面發表 | Sino–French Workshop on Bioorganic and Medicinal Chemistry | |
2 | 098 | 1 | 2009 | 10 | 黃建智 | Synthesis and Structure–Activity Relationship of 3-O-Acylated (–)-Epigallocatechins as 5α-Reductase Inhibitors | 是 | 第一順位 | 書面發表 | Huang, J.-J.; Lee, Y.-S.; Liao, C.-B.; Chen, P. | |
3 | 098 | 1 | 2009 | 12 | J.-J. Huang et. al | Development of Tetrahydro-1H-indol-2-ylmethyleneindolin-2-ones as Aurora Kinase Inhibitors | 是 | 其他 | 壁報發表 | IT’s 7th Annual Congress of International Drug Discovery Science and Technology | |
4 | 100 | 1 | 2011 | 9 | J.-J. Huang et. al | Discovery of Dual B-Raf and EGFR Inhibitors | 是 | 第一順位 | 口頭發表 | Senior Workshop: Advanced Version of WOCJC | |
5 | 104 | 1 | 2015 | 12 | Huang, J.-J. | Discovery of 4-Aryl-N-arylcarbonyl-2-aminothiazoles as Hec1/Nek2 Inhibitors. Part I: Optimization of In Vitro Potencies and Pharmacokinetic Properties | 是 | 第一順位 | 書面發表 | The 25th ISHC Congress | |
6 | 104 | 2 | 2016 | 4 | Jiann-Jyh Huang* et al. | Discovery of Novel Nek2/Hec1 Inhibitor TAI-95 Tosylate | 是 | 第一順位 | 壁報發表 | The 12th International Symposium on Organic Reactions | |
7 | 105 | 1 | 2016 | 8 | 黃建智 | Discovery of TAI-95 tosylate, the first-in-class anti-cancer lead candidate targeting Nek2/Hec1 interaction | 是 | 第一順位 | 壁報發表 | 2016台灣藥學會藥物化學研討會 | |
8 | 106 | 1 | 2017 | 12 | Min-Sian Huang, Yu-Fen Chen, Jo Chu Lin, Ying-Shuen Lee, Shih-Hsien Chuang, Jiann-Jyh Huang | Synthesis of Pyrrole–Indolin-2-ones as Multi-Kinase Inhibitors | 是 | 其他 | 壁報發表 | 2017中國化學會年會 | |
9 | 106 | 1 | 2017 | 12 | Ying-Shuan E. Lee ...// ... Jiann-Jyh Huang | Discovery of 4-Aryl-N-arylcarbonyl-2-aminothiazoles as Hec1/Nek2 Inhibitors. Part I: Optimization of In Vitro Potencies and Pharmacokinetic Properties | 是 | 第一順位 | 壁報發表 | 2017中國化學會年會 | |
10 | 106 | 1 | 2017 | 12 | Ying-Shuan E. Lee, Wen Yun Hsueh, Yi-Ling Liu, Bo-Syun Huang...//... Jiann-Jyh Huang | Discovery of Hec1/Nek2 Inhibitor First-in-Class Clinical Candidate TAI-95 | 是 | 其他 | 壁報發表 | 2017中國化學會年會 | |
11 | 106 | 1 | 2017 | 12 | Yu-Sheng Gao...//...Jiann-Jyh Huang* | Development of Novel Quinolinone Derivatives as New Anti-cancer Drugs | 是 | 其他 | 壁報發表 | 2017中國化學會年會 | |
12 | 107 | 1 | 2018 | 11 | 黃建智 | Copper(I)-Catalyzed Nitrile-Addition/N-Arylation Ring-Closure Cascade: Synthesis of 5,11-Dihydro-6H-indolo〔3,2-c〕quinolin- 6-ones as Topoisomerase-I Inhibitors with Potent In Vitro and In Vivo Antitumor Activities | 是 | 第一順位 | 壁報發表 | The 13th International Conference on Cutting-Edge Organic Chemistry in Asia (ICCEOCA-13) and the 4th | |
13 | 108 | 1 | 2019 | 9 | Jiann-Jyh Huang | A New Cascade Reaction for the Synthesis of 5,11-Dihydro-6H-indolo〔3,2-c〕quinolin-6-ones as Topoisomerase-I Inhibitors | 是 | 第一順位 | 壁報發表 | 27th International Society of Heterocyclic Chemistry Congress | |
學術活動(共計56筆) |
序號 | 學年度 | 學期 | 年度 | 月份 | 活動分類 | 活動名稱 | 活動地點/期刊學報/比賽名稱 |
1 | 104 | 1 | 2015 | 08 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
2 | 104 | 1 | 2015 | 08 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
3 | 104 | 1 | 2015 | 08 | 學術期刊論文審查 | Anti-Cancer Agents in Medicinal Chemistry期刊審查 | Anti-Cancer Agents in Medicinal Chemistry |
4 | 104 | 1 | 2015 | 09 | 學術期刊論文審查 | Molbank期刊審查 | Molbank |
5 | 104 | 1 | 2015 | 09 | 學術期刊論文審查 | Synthetic Communications期刊審查
| Synthetic Communications |
6 | 104 | 1 | 2015 | 11 | 主編、副主編 | Synthetic Communications期刊審查 | Synthetic Communications |
7 | 104 | 2 | 2016 | 02 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
8 | 104 | 2 | 2016 | 02 | 學術期刊論文審查 | Molecules期刊審查 | Molecules |
9 | 104 | 2 | 2016 | 03 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
10 | 104 | 2 | 2016 | 04 | 學術期刊論文審查 | Journal of Medicinal Chemistry期刊審查 | Journal of Medicinal Chemistry |
11 | 104 | 2 | 2016 | 05 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
12 | 104 | 2 | 2016 | 07 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
13 | 105 | 1 | 2016 | 08 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
14 | 105 | 1 | 2016 | 10 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
15 | 105 | 1 | 2016 | 10 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
16 | 105 | 1 | 2016 | 11 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
17 | 105 | 1 | 2016 | 11 | 學術期刊論文審查 | Heteroatom Chemistry期刊審查 | Heteroatom Chemistry |
18 | 105 | 1 | 2016 | 12 | 學術期刊論文審查 | Environmental Chemistry Letters期刊審查 | Environmental Chemistry Letters |
19 | 105 | 1 | 2017 | 01 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
20 | 105 | 1 | 2017 | 01 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
21 | 105 | 2 | 2017 | 02 | 學術期刊論文審查 | Journal of the Chinese Chemical Society期刊審查 | Journal of the Chinese Chemical Society |
22 | 105 | 2 | 2017 | 02 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
23 | 105 | 2 | 2017 | 03 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
24 | 105 | 2 | 2017 | 04 | 學術期刊論文審查 | Chemical Communications期刊審查 | Chemical Communications |
25 | 105 | 2 | 2017 | 04 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
26 | 105 | 2 | 2017 | 05 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
27 | 106 | 1 | 2017 | 08 | 學術期刊論文審查 | Scientific Reports期刊審查 | Scientific Reports |
28 | 106 | 1 | 2017 | 08 | 學術期刊論文審查 | Molecules期刊審查 | Molecules |
29 | 106 | 1 | 2017 | 08 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
30 | 106 | 1 | 2017 | 09 | 學術期刊論文審查 | Molecules期刊審查 | Molecules |
31 | 106 | 1 | 2017 | 11 | 學術期刊論文審查 | Molbank期刊審查 | Molbank |
32 | 106 | 1 | 2018 | 01 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
33 | 106 | 2 | 2018 | 02 | 學術期刊論文審查 | Molecules期刊審查 | Molecules |
34 | 106 | 2 | 2018 | 04 | 學術期刊論文審查 | Journal of the Chinese Chemical Society期刊審查 | Journal of the Chinese Chemical Societ |
35 | 106 | 2 | 2018 | 04 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
36 | 106 | 2 | 2018 | 04 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
37 | 106 | 2 | 2018 | 05 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
38 | 106 | 2 | 2018 | 05 | 學術期刊論文審查 | Molecules期刊審查 | Molecules |
39 | 106 | 2 | 2018 | 06 | 學術期刊論文審查 | Molecules期刊審查 | Molecules |
40 | 106 | 2 | 2018 | 07 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
41 | 106 | 2 | 2018 | 07 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
42 | 106 | 2 | 2018 | 07 | 學術期刊論文審查 | Journal of the Chinese Chemical Society期刊審查 | Journal of the Chinese Chemical Society |
43 | 107 | 1 | 2018 | 08 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
44 | 107 | 1 | 2019 | 01 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
45 | 107 | 2 | 2019 | 06 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
46 | 107 | 2 | 2019 | 07 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
47 | 108 | 1 | 2019 | 08 | 學術期刊論文審查 | Journal of Medicinal Chemistry期刊審查 | Journal of Medicinal Chemistry |
48 | 108 | 1 | 2019 | 09 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
49 | 108 | 1 | 2019 | 10 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
50 | 108 | 1 | 2019 | 11 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
51 | 108 | 1 | 2019 | 12 | 學術期刊論文審查 | Current Topics in Medicinal Chemistry期刊審查 | Current Topics in Medicinal Chemistry |
52 | 108 | 1 | 2020 | 01 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
53 | 108 | 2 | 2020 | 02 | 學術期刊論文審查 | Current Topics in Medicinal Chemistry期刊審查 | Current Topics in Medicinal Chemistry |
54 | 108 | 2 | 2020 | 03 | 學術期刊論文審查 | Molecules期刊審查 | Molecules |
55 | 108 | 2 | 2020 | 03 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |
56 | 108 | 2 | 2020 | 03 | 學術期刊論文審查 | Synthetic Communications期刊審查 | Synthetic Communications |