研究成果列表
單位名稱生化科技學系教師姓名林芸薇
教師分級教授專兼任專任
在校狀態在職行政職務學生事務處學生職涯發展中心主任

期刊論文(共計49筆)
序號學年度學期年度月份作者題目通訊作者作者順位期刊名稱卷數頁數關鍵字
1091120031Lin, Y.-W., Chuang, S.-M., and Yang, J.-L.Persistent activation of ERK1/2 by lead acetate increase nucleotide excision repair synthesis and confers anti-cytotoxicity and anti-mutagenicity. 其他 Carcinogenesis24 53-61   
2091220036 Lin, Y.-W., Chuang, S.-M., and Yang, J.-L.ERK1/2 achieves sustained activation by stimulating MAPK phosphatase-1 degradation via the ubiquitin-proteasome pathway. 第一順位J. Biol. Chem.278 21534-21541   
3094120061Lin, Y.-W. and Yang, J.-L. Proteolysis of Dual-Specificity MAPK Phosphatase MKP-1/CL100/DUSP1 via ERK Phosphorylation and SCFSkp2 Ubiquitination. 第一順位J. Biol. Chem.281 915-926  
4096120081Li JP, Wang CY, Tang YA, Lin YW, Yang JL*.Role of extracellular signal-regulated kinase (ERK) signaling in nucleotide excision repair and genotoxicity in response to As(III) and Pb(II)其他Pure Appl. Chem.80 2735-2750  
50971200811Ko JC, Hong JH, Wang LH, Cheng CM, Ciou SC, Lin ST, Jheng MY, Lin YW*Role of repair protein Rad51 in regulating the response to gefitinib in human non-small cell lung cancer cells.其他Molecular Cancer Therapeutics3632-41  
6096220085Ko JC, Hong JH, Wang LH, Lin YW*The role of repair protein Rad51 in synergistic cytotoxicity and mutagenicity induced by epidermal growth factor receptor inhibitor (Gefitinib, IressaR) and benzo(a)pyrene in human lung cancer.其他Experimental Cell Research314 1881-91  
7096220087Ko JC, Ciou SC, Cheng CM, Wang LH, Hong JH, Jheng MY, Ling ST, Lin YW*Involvement of Rad51 in cytotoxicity induced by epidermal growth factor receptor inhibitor (gefitinib, IressaR) and chemotherapeutic agents in human lung cancer cells.其他Carcinogenesis29 1448-58  
8097120088Wang CY, Lin YW, Yang JLActivation of protein kinase Calpha signaling prevents cytotoxicity and mutagenicity following lead acetate in CL3 human lung cancer cells.第二順位Toxicology250 55-61   
9097120088Chuang SM, Wang LH, Hong JH, Lin YW*Induction of Rad51 protein levels by p38 MAPK decreases cytotoxicity and mutagenicity in benzo(a)pyrene-exposed human lung cancer cells.其他Toxicology and Applied Pharmacology230 290-7  
100981200912Huang S, Chueh PJ, Lin YW, Shih TS, Chuang SMDisturbed mitotic progression and genome segregation are involved in cell transformation mediated by nano-TiO2 long-term exposure.第三順位Toxicol Appl Pharmacol241 182-94   
11098120098Ko JC, Ciou SC, Jhan JY, Cheng CM, Su YJ, Chuang SM, Lin ST, Chia-Che Chang, Lin YW*. Roles of MKK1/2-ERK1/2 and PI3K-AKT signaling pathways in erlotinib-induced Rad51 suppression and cytotoxicity in human non-small cell lung cancer cells. 其他Molecular Cancer Research 1378-89   
12098120099Chen RS, Jhan JY, Su YJ, Lee WT, Cheng CM, Ciou SC, Lin ST, Chuang SM, Ko JC, and Lin YW*. Emodin enhances gefitinib-induced cytotoxicity via Rad51 downregulation and ERK1/2 inactivation.其他Exp Cell Res 315 2658-2672   
13098120099Ko JC, Wang LH, Jhan JY, Ciou SC, Hong JH, Lin ST, Lin YW*. The role of celecoxib in Rad51 expression and cell survival affected by gefitinib in human non-small cell lung cancer cells其他Lung Cancer 65 290-298  
140991201012Tsai MS, Kuo YH, Chiu YF, Su YC, Lin YW*Downregulation of Rad51 expression overcomes drug resistance to gemcitabine in human non-small cell lung cancer cells.其他The Journal of Pharmacology and Experimental Therapeutics 335 830-840   
15098220102Ko JC, Su YJ, Lin ST, Jhan JY, Ciou SC, Cheng CM, Lin YW*.Suppression of ERCC1 and Rad51 expression through ERK1/2 inactivation is essential in emodin-mediated cytotoxicity in human non-small cell lung cancer cells.其他Biochemical Pharmacology 79 655-664   
16098220104Su YJ, Tsai MS, Kuo YH, Chiu YF, Cheng CM, Lin ST, Lin YW*. Role of Rad51 Down-Regulation and Extracellular Signal-Regulated Kinases 1 and 2 Inactivation in Emodin and Mitomycin C-Induced Synergistic Cytotoxicity in Human Non–Small-Cell Lung Cancer Cells.其他Molecular Pharmacology 77 633-643   
17098220104Lin YW, Yang FJ, Chen CL, Lee WT, Chen RS*. Free radical scavenging activity and antiproliferative potential of Polygonum cuspidatum root extracts. 第一順位Journal of Natural Medicines64 146-152   
18099120108Ko JC, Su YJ, Lin ST , Jhan JY, Ciou SC, Cheng CM, Chiu YF, Kuo YH, Tsai MS, Lin YW*. Emodin enhances cisplatin-induced cytotoxicity via down-regulation of ERCC1 and inactivation of ERK1/2.其他Lung Cancer 69 155-164   
19099220113Ko JC, Tsai MS, Kuo YH, Chiu YF, Su YC, Lin YW*. Modulation of Rad51, ERCC1, and thymidine phosphorylase by emodin resulte in synergistic cytotoxic effect in combination with capecitabine.其他Biochemical Pharmacology81 680-690  
20099220117Ko JC, Tsai MS, Chiu YF, Weng SH, Kuo YH, Lin YW*Up-regulation of ERK1/2-dependent thymidylate synthase and thymidine phosphorylase contributes to cisplatin resistance in human non-small cell lung cancer cells其他The Journal of Pharmacology and Experimental Therapeutics 338 184-194  
21099220117Tsai MS, Weng SH, Kuo YH, Chiu YF, Lin YW*.Synergistic effect of curcumin and cisplatin via downregulation of thymidine phosphorylase and excision repair cross-complementary 1 (ERCC1).其他Molecular Pharmacology80 136-146  
22100120119Shen YH, Chen BR, Cherng SH, Chueh PJ, Tan X, Lin YW, Lin JC, Chuang SM*.Cisplatin transiently up-regulates hHR23 expression through enhanced translational efficiency in A549 adenocarcinoma cells.其他Toxicol Lett.205 341-350  
23100120119Ko JC, Tsai MS, Weng SH, Kuo YH, Chiu YF, Lin YW*.Curcumin enhances the mitomycin C-induced cytotoxicity via downregulation of MKK1/2-ERK1/2-mediated Rad51 expression in non-small cell lung cancer cells. 其他Toxicol Appl Pharmacol255 327-38  
2410112012123. Ko JC, Chen HJ, Huang YC, Tseng SC, Weng SH, Wo TY, Huang YJ, Chiu HC, Tsai MS, Chiou Y.Y., Lin YHSP90 inhibition induces cytotoxicity via down-regulation of Rad51 expression and DNA repair capacity in non-small cell lung cancer cells.其他Regulatory Toxicology and Pharmacology64 415-424  
25100220123Weng SH, Tsai MS, Chiu YF, Kuo YH, Chen HJ, Lin YW*Enhancement of mitomycin C-induced cytotoxicity by curcumin results from downregulation of MKK1/2-ERK1/2-mediated thymidine phosphorylase expression.其他Basic Clinical Pharmacology Toxicology110 298-306  
26100220123Tsai MS, Weng SH, Chen HJ, Chiu YF, Huang YC, Tseng SC, Kuo YH, Lin YW*Inhibition of p38 MAPK–dependent excision repair cross-complementing 1 expression decreases the DNA repair capacity to sensitize lung cancer cells to etoposide.其他Molecular Cancer Therapeutics11 561-571  
27100220127Weng SH, Tseng SC, Huang YC, Chen HJ, Lin YW*. Inhibition of thymidine phosphorylase expression by using an HSP90 inhibitor potentiates the cytotoxic effect of cisplatin in non-small-cell lung cancer cells.其他Biochemical Pharmacology84 126-136  
28100220127Lu CH, Lin SC, Yang SY, Pan MY, Lin YW, Hsu CY, Wei YH, Chang JS, Chang CC*.Toxicol Lett.其他Toxicol Lett.121 83-89  
291021201312Chen RS, Ko JC, Chiu HC, Wo TY, Huang YJ, Tseng SC, Chen HJ, Huang YC, Jian YJ, Lee WT, Lin YW*.Pemetrexed downregulates ERCC1 expression and enhances cytotoxicity effected by resveratrol in human nonsmall cell lung cancer cells 其他Naunyn Schmiedebergs Archives of Pharmacology386 1047-1059  
301021201312Ko JC, Chiu HC, Wo TY, Huang YJ, Tseng SC, Huang YC, Chen HJ, Syu JJ, Chen CY, Jian YT, Jian YJ, Inhibition of p38 MAPK-dependent MutS homologue-2 (MSH2) expression by metformin enhances gefitinib-induced cytotoxicity in human squamous lung cancer cells其他Lung Cancer 82 397-406  
31101220132Tseng SC, Huang YC, Chen HJ, Chiu HC, Huang YJ, Wo TY, Weng SH, Lin YW*Metformin-mediated downregulation of p38 mitogen-activated protein kinase-dependent excision repair cross-complementing 1 decreases DNA repair capacity and sensitizes human lung cancer cells to paclitaxel.其他Biochemical Pharmacology85 583-594  
32101220137Ko JC, Huang YC, Chen HJ, Tseng SC, Chiu HC, Wo TY, Huang YJ, Weng SH, Chiou Y.Y., Lin YW*Ko JC, Huang YC, Chen HJ, Tseng SC, Chiu HC, Wo TY, Huang YJ, Weng SH, Chiou Y.Y., Lin YW*其他Basic Clinical Pharmacology Toxicology113 56-65  
33102220143Ko JC, Chiu HC, Syu JJ, Jian YJ, Chen CY, Jian YT, Huang YJ, Wo TY, Lin YW*Tamoxifen enhances erlotinib-induced cytotoxicity through down-regulating AKT-mediated thymidine phosphorylase expression in human non-small-cell lung cancer cells.其他Biochemical Pharmacology88 119-127  
34102220144Tung CL, Chiu HC, Jian YJ, Jian YT, Chen CY, Syu JJ, Wo TY, Huang YJ, Tseng SC, Lin YW*Down-regulation of MSH2 expression by an Hsp90 inhibitor enhances pemetrexed-induced cytotoxicity in human non-small-cell lung cancer cells其他Experimental Cell Research322 345-354  
35103120151Ko JC, Chiu HC, Syu JJ, Chen CY, Jian YJ, Huang YJ, Wo TY, Jian YJ, Chang PY, Wang TJ, and Lin YWDown-regulation of MSH2 expression by Hsp90 inhibition enhances cytotoxicity affected by tamoxifen in human lung cancer cells.其他Biochemical and Biophysical Research Communications 456 506-512  
361041201510Ko JC, Wang TJ, Chang PY, Syu JJ, Chen JC, Chen CY, Jian YT, Jian YJ, Zheng HY, Chen WC, Lin YW Minocycline enhances mitomycin C-induced cytotoxicity through down-regulating ERK1/2-mediated Rad51 expression in human non-small cell lung cancer cells.其他Biochemical Pharmacology97 331-340  
371041201512Ko JC, Syu JJ, Chen JC, Wang TJ, Chang PY, Chen CY, Jian YT, Jian YJ, and Lin YW*Resveratrol enhances etoposide-induced cytotoxicity through down-regulating ERK1/2 and AKT-mediated X-ray repair cross-complement group 1 (XRCC1) protein expression in human non-small-cell lung cancer cells其他Basic Clinical Pharmacology Toxicology117 383-391  
38103220155Tung CL, Jian YJ, Syu JJ, Wang TJ, Chang PY, Chen CY, Jian YT, and Lin YW*Down-regulation of ERK1/2 and AKT-mediated X-ray repair cross-complement group 1 protein (XRCC1) expression by Hsp90 inhibition enhances the gefitinib-induced cytotoxicity in human lung cancer cells其他Experimental Cell Research334 126-135  
391051201612Ko JC, Zheng HY, Chen WC, Peng YS, Wu CH, CL Wei, JC Chen, and Lin YW*Salinomycin enhances cisplatin-induced cytotoxicity in human lung cancer cells via down-regulation of AKT-dependent thymidylate synthase expression. 其他Biochemical Pharmacology 122 90-98  
40104220163Tung CL, Jian YJ, Chen JC, Wang TJ, Chen WC, Zheng HY, Chang PY, Liao KS, and Lin YW*Curcumin downregulates p38 MAPK–dependent X-ray repair cross-complement group 1 (XRCC1) expression to enhance cisplatin-induced cytotoxicity in human lung cancer cells其他Naunyn-Schmiedebergs Archives of Pharmacology389 657-66  
411042201642. Ko JC, Chen JC, Wang TJ, Zheng HY, Chen WC, Chang PY, and Lin YW*Astaxanthin down-regulates Rad51 expression via inactivation of AKT kinase to enhance mitomycin C-induced cytotoxicity in human non-small cell lung cancer cells其他Biochemical Pharmacology105 91-100  
42105120169Liao KS, Wei CL, Chen JC, Zheng HY, Chen WC, Wu CH, Wang TJ, Peng YS, Chang PY, and Lin YW*Astaxanthin enhances pemetrexed-induced cytotoxicity by downregulation of thymidylate synthase expression in human lung cancer cells. 2016 Sep 28;81:353-361. 其他Regulatory Toxicology and Pharmacology 81 353-361  
431061201712Ko JC, Peng YS, Wu CH, Chen JC, Zheng HY, Lin YC, Ma PF, Chen WC, and Lin YW*Down-Regulation of MutS Homolog 2 (MSH2) Expression by Curcumin Enhances Cytotoxicity Induced by Gemcitabine in Human Lung Adenocarcinoma Cells.其他Epidemiology1000332  
44106120178Tung CL, Chen JC, Wu CH, Peng YS, Chen WC, Zheng HY, Jian YJ, Wei CL, Cheng YT, and Lin YW*Salinomycin acts through reducing AKT-dependent thymidylate synthase expression to enhance erlotinib-induced cytotoxicity in human lung cancer cells其他Exp Cell Res357 59-66  
45106220186Chen JC, Ma PF, Lin YC, Wu CH, Peng YS, Zheng HY, Lin MC, Li YT, Lin YW*17-(Allylamino)-17-Demethoxygeldanamycin Enhances Etoposide-Induced Cytotoxicity via the Downregulation of Xeroderma Pigmentosum Complementation Group C Expression in Human Lung Squamous Cell Carcinoma Cells其他Pharmacology 102 91-104  
46107120189Chen JC, Wu CH, Peng YS, Zheng HY, Lin YC, Ma PF, Yen TC, Chen TY, Lin YW*Astaxanthin enhances erlotinib-induced cytotoxicity by p38 MAPK mediated xeroderma pigmentosum complementation group C (XPC) down-regulation in human lung cancer cells其他Toxicology Research1247–1256  
47107220192Ko JC, Chen JC, Chen TY, Yen TC, Ma PF, Lin YC, Wu CH, Peng YS, Zheng HY, Lin YW*Inhibition of thymidine phosphorylase expression by Hsp90 inhibitor potentiates the cytotoxic effect of salinomycin in human non-small-cell lung cancer cells其他Toxicology417 54-63  
48107220193Chen JC, Ko JC, Yen TC, Chen TY, Lin YC, Ma PF, and Lin YW*Capsaicin enhances erlotinib-induced cytotoxicity via AKT inactivation and excision repair cross-complementary 1 (ERCC1) down-regulation in human lung cancer cells其他Toxicology Research459-470  
49108220203Ko JC, Chen JC, Yen TC, Chen TY, Ma PF, Lin YC, Cheng HH, Taso YC, and Lin YW*Nitroglycerin enhances cisplatin-induced cytotoxicity via AKT inactivation and thymidylate synthase down-regulation in human lung cancer cells其他Pharmacology105 209-224  

會議論文(共計36筆)
序號學年度學期年度月份作者題目通訊作者作者順位發表性質會議論文集或研討會名稱地點
10901200110Lin, Y.-W., and Yang, J.-L. Activation of ERK by lead acetate confers anti-cytotoxixity and anti-mutagenicity in cultured human cells.第一順位壁報發表 8th International Conference on Environmental Mutagens Shizuoka, Japan 
20901200110Yang, J.-L., Liou, G.-Y., Lin, Y.-W., Chuang, S.-M., and Chen, R.-H. Roles of three mitogen-activated protein kinase in UV-induced mutagenesis.其他壁報發表  8th International Conference on Environmental Mutagens Shizuoka, Japan 
3093220057Yun-Wei Lin and Jai-Ling Yang. Proteolysis of Dual-Specificity MAPK Phosphatase MKP-1/CL100/DUSP1 via ERK Phosphorylation and SCFSkp2 Ubiquitination. 第一順位壁報發表 FASEB Summer Research Conferences Snowmass, Colorado 
40961200711Lyu-Han Wang, Jhao-Hao Hong, and Yun-Wei Lin.p38 MAPK activation by benzo(a)pyrene increase Rad51 protein level and prevent cytotoxicity and mutagenicity in human lung cancer cells.其他書面發表 The 1st International Cancer Symposium Taiwan, China Medical University and Hospital 
5096220084Jen-Chung Ko, Jhao-Hao Hong, Lyu-Han Wang and Yun-Wei Lin.The role of repair protein Rad51 in synergistic cytotoxicity and mutagenicity induced by epidermal growth factor receptor inhibitor (Gefitinib, IressaR) and benzo(a)pyrene in human lung cancer.其他壁報發表  American Association for Cancer Research Annual Meeting San Diego Convention Center, San Diego, CA. 
6096220084Show-Mei Chuang, Lyu-Han Wang, Jhao-Hao Hong, and Yun-Wei Lin. Induction of Rad51 protein levels by p38 MAPK decreases cytotoxicity and mutagenicity in benzo(a)pyrene-exposed human lung cancer cells. 其他書面發表 American Association for Cancer Research Annual Meeting. San Diego Convention Center, San Diego, CA. 
7096220085Jhao-Hao Hong and Yun-Wei Lin.The Role of Rad51 in Benzo(a)pyrene and Epidermal Growth Factor Receptor Inhibitor (Gefitinib, Iressa) Induced Synergistic Cytotoxicity in Human Lung Cancer. 其他書面發表 The 23rd Joint Annual Conference of Biomedical sciences  National Defence Medical Center, Taiwan.  
8096220085Lyu-Han Wang and Yun-Wei Lin.The Role of p38 MAPK and ATM/ATR Signal in Benzo(a)pyrene Induced Rad51 Gene and Protein Expression in Human Lung Cancer Cells.其他書面發表 The 23rd Joint Annual Conference of Biomedical sciences  National Defence Medical Center, Taiwan. 
90981200911Yun-Wei Lin, Jen-Chung Ko, Ying-Jhen Su. Roles of MKK1/2-ERK1/2 and PI3K-AKT signaling pathways in erlotinib-induced Rad51 suppression and cytotoxicity in human non-small cell lung cancer cells.其他壁報發表 Biotechnology Taiwan 2009 Conference Taipei, Taiwan 
100981200911Ying-Jhen Su, Szu-Ting Lin, Yun-Wei Lin.Suppression of ercc1 and rad51 expression through erk1/2 inactivation is essential in emodin-mediated cytotoxicity in human lung cancer cells.其他壁報發表 Biotechnology Taiwan 2009 Conference Taipei, Taiwan 
110981200911Min-Shao Tsai, Ying-Jhen Su, Szu-Ting Lin, Yu-Fan Chiu, Ya-Hsun Kuo, Yun-Wei Lin. Emodin enhances cisplatin-induced cytotoxicity via down-regulation of ercc1 and inactivation of erk1/2 in human non-small cell lung cancer cells.其他壁報發表 Biotechnology Taiwan 2009 Conference Taipei, Taiwan 
12097220094Jen-Chung Ko, Chao-Min Cheng, Shih-Ci Ciou, Jhih-Yuan Jhan, Ying-Jhen Su, Show-Mei Chuang, Szu-Ting Role of MKK1/2-ERK1/2 and PI3K-AKT signaling in erlotinib decrease Rad51 expression and cell survival in human non-small cell lung cancer cells.其他壁報發表 American Association for Cancer Research Annual Meeting Colorado Convention Center, Denver, CO.  
13097220094Jhih-Yuan Jhan , Lyu-Han Wang, Shih-Ci Ciou and Yun-Wei Lin. Role of Celecoxib in Rad51 Expression and Cell Survival Affected by Gefitinib in Human Non-Small Cell Lung Cancer Cells.其他壁報發表 The 24th Joint Annual Conference of Biomedical Science  Taiwan 
14097220094Chao-Min Cheng, Shih-Ci Ciou, Yun-Wei Lin.Rad51 Regulate the Different Response to Gefitinib in Human Non-Small Cell Lung Cancer Cells.其他壁報發表 24th Joint Annual Conference of Biomedical Science Taiwan  
15097220094Shih-Ci Ciou, Chao-Min Cheng, Yun-Wei Lin. Involvement of Rad51 in Cytotoxicity induced by Gefitinib and Chemotherapeutic agents in Human Lung Cancer Cells. 其他壁報發表 The 24th Joint Annual Conference of Biomedical Science Taiwan 
16098220102Su YJ, Tsai MS, Kuo YH, Chiu YF, Cheng CM, Lin ST, Lin YW. Role of Rad51 downregulation and ERK1/2 inactivation in emodin and mitomycin C-induced synergistic cytotoxicity in human non-small cell lung cancer cells.其他壁報發表 AACR/JCA Joint Conference: Cancer Genomics, Epigenomics, and the Development of Novel Therapeutics. Hilton Waikoloa Village, Waikoloa, Hawaii 
17099220113Shao-Hsing Weng, Min-Shao Tsai, Yu-Fan Chiu, Ya-Hsun Kuo, and Yun-Wei Lin.Curcumin sensitizes non-small cell lung cancer cells to cisplatin induced cytotoxicity via thymidine phosphorylase and ERCC1 downregulation. 第一順位壁報發表 The 26th Joint Annual Conference of Biomedical Sciences  
18099220113Min-Shao Tsai, Ya-Hsun Kuo, Yu-Fan Chiu, Shao-Hsing Weng, and Yun-Wei Lin.Inhibition of Rad51 and ERCC1 and increase of thymidine phosphorylase by emodin enhance capecitabine-induced cytotoxicity in human non-small cell lung cancer cells.其他壁報發表 The 26th Joint Annual Conference of Biomedical Sciences  
19099220114Min-Shao Tsai, Ya-Hsun Kuo, Yu-Fan Chiu, Ying-Chen Su, and Yun-Wei Lin. Downregulation of Rad51 expression overcomes drug resistance to gemcitabine in human non-small cell lung cancer cells.第一順位壁報發表 Physiology Symposium 2011  
20099220114Yu-Fan Chiu, Min-Shao Tsai, Shao-Hsing Weng, Ya-Hsun Kuo, Yun-Wei Lin. Up-regulation of ERK1/2-dependent thymidylate synthase and thymidine phosphorylase contributes to cisplatin resistance in human non-small cell lung cancer cells.其他壁報發表 Physiology Symposium 2011  
21099220114Min-Shao Tsai, Yu-Fan Chiu, Shao-Hsing Weng, Ya-Hsun Kuo, and Yun-Wei Lin. Thymidylate synthase and thymidine phosphorylase expression contributes to cisplatin resistance.其他壁報發表 102nd AACR Annual Meeting.  
22100220123Yun-Wei Lin, Shao-Hsing Weng, Jen-Chung Ko, Huang-Jen Chen, Sheng-Chieh Tseng, Yu-Ching Huang, MHSP90 inhibition induced cytotoxicity via downregulation of Rad51 expression and DNA repair capacity in non-small cell lung cancer cells. 第一順位壁報發表 AACR Annual Meeting 2012  
23100220123Yu-Ching Huang, Sheng-Chieh Tseng, Huang-Jen Chen, Shao-Hsing Weng, and Yun-Wei Lin*.HSP90 inhibition induced cytotoxicity through down-regulation of Rad51 and thymidine phosphorylase expression in human non-small cell lung cancer cells. 其他壁報發表 The 27th Joint Annual Conference of Biomedical Sciences  
24100220125Yu-Ching Huang, Sheng-Chieh Tseng, Shao-Hsing Weng, Huang-Jen Chen, and Yun-Wei LinDown-regulation of thymidine phosphorylase expression by 17-AAG enhances the cytotoxic effect of cisplatin in human lung cancer cells.其他壁報發表 The International Symposium in Commemoration of the 5th Anniversary of College of Life Sciences  
25101220134林芸薇Role of ERCC1 in metformin enhancing paclitaxel-induced cytotoxicity.其他壁報發表 AACR Annual Meeting 2013 Washington Convention Center, Washington, DC. 
26101220134林芸薇Metformin induces cytotoxicity by TP and ERCC1 decrease.其他壁報發表 AACR Annual Meeting 2013. Washington Convention Center, Washington, DC.  
27101220135林芸薇Role of pemetrexed in DNA repair capacity and cell survival affected by resveratrol.其他壁報發表 IBMS-JSBMR 2013.   
281051201611Chia-Hung Wu, Hao-Yu Zheng, Wen-Ching Chen, Yi-Shuan Peng, and Yun-Wei LinRole of thymidylate synthase expression in astaxanthin and pemetrexed-induced cytotoxicity in human non-small cell lung cancer cells其他壁報發表 第六屆國際植物化合物暨疾病預防與功能評估研討會 嘉義大學 
291051201611Yi-Shuan Peng, Hao-Yu Zheng, Wen-Ching Chen, Chia-Hung Wu, Chia-Li Wei, Jyh-Cheng Chen, and Yun-WeiSalinomycin enhances cisplatin-induced cytotoxicity in human lung cancer cells via down-regulation of thymidylate synthase expression其他壁報發表 第六屆國際植物化合物暨疾病預防與功能評估研討會  
30106220183Yuan -Cheng Lin, Jyh -Cheng Chen, Peng -Fang Ma, Chia -Hung Wu, Yi -Shuan Peng, Hao -Yu ZhengCurcumin Enhances Gemcitabine-induced Cytotoxicity Via Down-Regulation of MutS Homolog 2 (MSH2) Expression in Human Lung Adenocarcinoma A549 Cells其他壁報發表 第33屆生物醫學聯合學術年會  
31106220183Peng-Fang Ma, Jyh-Cheng Chen, Yuan-Cheng Lin, Chia-Hung Wu, Yi-Shuan Peng, Hao-Yu Zheng, and Yun-Astaxanthin enforces cytotoxicity via p38 MAPK mediated Xeroderma pigmentosum complementation group C (XPC) down-regulation in human lung cancer cells其他壁報發表 第33屆生物醫學聯合學術年會  
321081201912Yun-Wei LinRole of DNA repair proteins in lung cancer chemotherapy 第一順位口頭發表 DDSG symposium 日本岩手 
33107220193陳姿吟Tzu-Ying Chen, 林芸薇 Yun -Wei Lin*Inhibition of thymidine phosphorylase expression by hsp90 inhibitor potentiates the cytotoxic effect of salinomycin in human non-small-cell lung cancer cells.其他壁報發表 第34屆生物醫學聯合學術年會  
34107220193顏廷涓 Ting-Chuan Yen, 林芸薇 Yun -Wei Lin*Capsaicin enhances erlotinib-induced cytotoxicity via AKT inactivation and excision repair cross-complementary 1 (ERCC1) down-regulation in human lung cancer cells.其他壁報發表 第34屆生物醫學聯合學術年會  
35107220197Lin YWNitroglycerin induced cytotoxicity in human lung cancer cells via AKT inactivation and thymidylate synthase (TS) down-regulation.其他壁報發表 23rdGlobal Annual Oncologists Meeting  
36108220203Chen JC, Ko JC, Cheng HH, Taso YC, Yen TC, Chen TY, and Lin YW*17-Allylamino-Demethoxygeldanamycin enhances bevacizumab-induced cytotoxicity via Xeroderma pigmentosum complementation group C (XPC) down-regulation in human lung cancer cells其他壁報發表 EACR-AACR Basic and Translational Research Conference 葡萄牙 

研究計畫(共計58筆)
備註欄說明:「教師研究計畫管理系統轉入之計畫」(係指依「國立嘉義大學產學合作計畫實施要點」第3點規定,與政府機關、法人、公民營事業機構、民間團體、學術研究機構等合作辦理有關事項,以本校名義與合作機構辦理簽約,其經費撥入本校之產學合作計畫。)
序號學年度學期年度月份參與性質委辦單位計畫名稱開始日期結束日期經費備註欄
1095120068總計畫主持人科技部探討多苯環芳香烴誘發持續性p38 MAPK活化的分子機轉2006/08/012007/07/311125000
2095120071計畫主持人科技部探討多苯環芳香經誘發持續性p38 MAPK 活化的分子機轉2006/11/012007/07/311125000
3095120071子計畫主持人行政院農業委員會洛神葵新品系植物機能性保健功能驗證研究2007/01/012007/12/31200000
4095220075總計畫主持人其他政府機關-其他政府單位人類肺腺癌與扁平上皮細胞癌對表皮生長因子受體抑制劑(艾瑞莎)有不同反應之分子機轉2007/05/012008/04/30500000
5096120078總計畫主持人科技部探討持續性p38 MAPK活化促進MKP-1蛋白質分解的分子機轉2007/08/012008/07/311020000
6096120081總計畫主持人其他政府機關-其他政府單位Cyclooxygenase-2 (COX-2)抑制劑(希樂葆)與表皮生長因子受體抑制劑(艾瑞莎)對人類非小細胞肺癌有相加成之細胞毒性的分子機轉2008/01/012008/12/15500000
7096120081總計畫主持人其他政府機關-其他政府單位修補蛋白Rad51在表皮生長因子受體抑制劑與多苯環芳香烴致癌物處理肺癌細胞後所誘發之細胞毒性與基因毒性的角色探討2008/01/012008/12/15500000
8097120088總計畫主持人科技部探索多苯環芳香烴調控Rad51基因與蛋白質表現之分子機制2008/08/012011/07/312700000
9097120091總計畫主持人其他政府機關-其他政府單位核酸修補蛋白Rad51在人類肺癌細胞對表皮生長因子受體抑制劑(Iressa,艾瑞莎)與化療藥物抗藥性的角色2009/01/012009/12/31500000
10097120091總計畫主持人其他政府機關-其他政府單位核酸修補蛋白Rad51及ERCC1在克服人類小細胞肺癌產生對表皮生長因子受體抑制劑及化療藥物抗藥性之角色探討 2009/01/012009/12/31500000
11098120101總計畫主持人其他政府機關-其他政府單位探索大黃素emodin與化療藥物cisplatin協力抑制人類非小細胞肺癌細胞存活的分子機轉2010/01/012010/12/31240000
12098120101總計畫主持人其他政府機關-其他政府單位胸腺嘧啶核甘酸合成酶抑制劑(Thymidylate Synthase inhibitor)與表皮生長因子受體抑制劑 (Erlotinib,得舒緩)合併處理人類扁平上皮細胞肺癌細胞具有加強毒殺效果之分子機轉2010/01/012010/12/31500000
13098120101總計畫主持人其他政府機關-其他政府單位核酸修補蛋白Rad51及ERCC1在大黃素抑制人類非小細胞肺癌細胞存活之角色探討 2010/01/012010/12/31500000
14099120108總計畫主持人科技部大黃素調控人類肺癌細胞內Rad51與ERCC1對抗表皮生長因子受體抑制劑與化療藥物抗藥性的分子機轉2010/08/012013/07/313708000
150991201008總計畫主持人科技部大黃素調控人類肺癌細胞內Rad51與ERCC1對抗表皮生長因子受體抑制劑與化療藥物抗藥性的分子機轉(1/3)2010/08/012013/07/311200000
161001201108總計畫主持人科技部大黃素調控人類肺癌細胞內Rad51與ERCC1對抗表皮生長因子受體抑制劑與化療藥物抗藥性的分子機轉(2/3)2011/08/012013/07/311320000
171002201207計畫主持人科技部薑黃素藉由誘導thymidine phosphorylase的向下調節以增加化療藥物致敏感性的分子機轉2012/07/012013/02/2847000
181011201208總計畫主持人科技部大黃素調控人類肺癌細胞內Rad51與ERCC1對抗表皮生長因子受體抑制劑與化療藥物抗藥性的分子機轉(3/3)2012/08/012013/07/311188000
191011201211計畫主持人教育部101學年度大專校院推動學校健康促進實施計畫2012/11/092013/07/31144000
201021201308計畫主持人科技部探索抑制熱休克蛋白90活性如何向下調控非小細胞肺癌細胞內ERCC1的表現與核酸修補能力進而增加化療藥物敏感性之分子機轉2013/08/012014/07/311150000
211021201308共同主持人科技部滅糖敏向下調控核酸代謝酵素thymidine phosphorylase表現在增加肺癌細胞對化療藥物順鉑與標靶藥物艾瑞莎敏感性的分子機轉2013/08/012014/07/31950000
221021201308共同主持人其他政府機關-其他政府基金(如國立大學)滅糖敏向下調控核酸代謝酵素thymidine phosphorylase表現在增加肺癌細胞對化療藥物順鉑與標靶藥物艾瑞莎敏感性的分子機轉(科技部共同主持人計畫)2013/08/012014/07/31475000
231022201407計畫主持人科技部大專生計畫:探討核酸代謝酵素thymidine phosphorylase在得舒緩增加諾瓦得士錠對人類非小肺癌細胞藥物敏感性的角色(指導學生:陳建宇)2014/07/012015/02/2847000
241032201507計畫主持人科技部大專生研究計畫:探索調節XRCC1鹼基缺失修復蛋白表現在拓樸異構酶抑制劑與白藜蘆醇協力毒殺非小型細胞肺癌細胞的分子機轉2015/07/012016/02/2948000
251041201508計畫主持人科技部雌性激素受體拮抗劑向下調控thymidine phosphorylase表現在增加表皮生長因子受體抑制劑與化療藥物毒殺非小細胞肺癌細胞的分子機轉2015/08/012016/07/31850000
261042201602計畫主持人行政院農業委員會農業試驗所嘉義農業試驗分所機能性水稻優質安全生產技術建立及加值產品研發2016/02/282016/11/301440000
271042201607計畫主持人其他民間企業團體-其他民間企業團體或個人嘉義大學生化科技學系攜手晁陽: 2016暑期綠能生態成長體驗營2016/07/012016/07/318800
281042201607科技部大專生計畫-蝦青素和絲裂黴素C藉向下調節Rad51表現協力誘導人類非小細胞肺癌細胞毒性之分子機轉(鄭皓妤)2016/07/012017/02/2848000
291042201607科技部大專生計畫-探索薑黃素向下調控XRCC1的表現並加強化療藥物順鉑誘導細胞毒性之分子機制(陳玟晴)2016/07/012017/02/2848000
301042201607計畫主持人科技部蝦青素和絲裂黴素C藉向下調節Rad51表現協力誘導人類非小細胞肺癌細胞毒性之分子機轉(鄭皓妤)2016/07/012017/02/2848000
31104220167計畫主持人科技部探索薑黃素向下調控XRCC1的表現並加強化療藥物順鉑誘導細胞毒性之分子機制(陳玟晴)2016/07/012017/02/2848000
321051201608計畫主持人科技部滅糖敏藉由MKK3/6-p38 MAPK 訊號失活所導致MSH2表現下降進而增加標靶藥物艾瑞莎毒殺肺癌細胞的角色:(科技部共同主持人)2016/08/012017/07/31521000
331052201707計畫主持人其他民間企業團體-其他民間企業團體或個人嘉義大學生化科技學系攜手晁陽-2017綠能食農產生態夏令營2017/07/012017/07/316600
341052201707科技部大專生計畫-蝦紅素藉由下調節胸線嘧啶合成酶的表現來增加愛寧達所誘導人類肺癌細胞毒性(吳佳鴻)2017/07/012018/02/2848000
351052201707計畫主持人科技部鹽黴素藉由下調節AKT依賴性的胸腺核苷酸合成酶表現來增強順鉑對人類肺癌細胞所產生的細胞毒性 (彭宜萱 )2017/07/012018/02/280
36105220177計畫主持人科技部蝦紅素藉由下調節胸線嘧啶合成酶的表現來增加愛寧達所誘導人類肺癌細胞毒性(吳佳鴻)2017/07/012018/02/2848000
371062201807計畫主持人科技部大專生計畫:薑黃素向下調節人類修補蛋白MSH2的表現量增強健擇(Gemcitabine)誘導人類肺癌細胞所產生的細胞毒性(指導學生:林園宸)2018/07/012019/02/2848000
381071201808計畫主持人科技部蝦紅素向下調控人類肺癌細胞內著色性乾皮互補組蛋白C表現在增加得舒緩毒殺非小細胞肺癌細胞的分子機轉2018/08/012019/07/311030000
391071201808計畫主持人科技部鹽黴素與硝化甘油導致胸腺嘧啶合成酶及乙醛去氫酶1A1表現下降在增加人類非小細胞肺癌細胞對於化療藥物順鉑敏感性之角色(共同主持人)2018/08/012019/07/31505000
401072201907計畫主持人科技部大專生計畫:探討辣椒素藉由向下調控切除修復交叉互補1 (ERCC1)修補蛋白表現來增加得舒緩(erlotinib)所誘導人類肺癌細胞毒性之分子機轉:(指導學生:顏廷涓)2019/07/012020/02/2848000
411072201907科技部大專生計畫:探討熱休克蛋白Hsp90抑制劑抑制胸腺嘧啶磷酸酶的表達增強鹽黴素對人類非小細胞肺癌細胞的毒性作用:(指導學生:陳姿吟)2019/07/012020/02/2848000
421081201908科技部探索抑制熱休克蛋白90活性如何向下調控人類肺癌細胞內著色性乾皮互補組蛋白C的表現與核酸修補能力進而增加化療藥物敏感性之分子機轉2019/08/012020/07/311279000
431081202001計畫主持人教育部高等教育深耕計畫「第一部分計畫書」附錄1:「提升高教公共性:完善就學協助機制,有效促進社會流動」2020/01/012020/12/319407000教師研究計畫管理系統轉入之計畫
441081202001計畫主持人教育部高等教育深耕計畫「第一部分計畫書」附錄2:「提升高教公共性:透過原住民族學生資源中心輔導原住民學生成效」2020/01/012020/12/31800000教師研究計畫管理系統轉入之計畫
451081202001計畫主持人教育部轉角遇見愛~品德行善CEO2020/01/012020/11/30112200教師研究計畫管理系統轉入之計畫
461081202001計畫主持人教育部教育部協助大專校院因應嚴重特殊傳染性肺炎影響衝擊補助計畫2020/01/152021/06/302091018教師研究計畫管理系統轉入之計畫
471082202002計畫主持人其他民間企業團體-其他基金(如基金會)嘉義大學「原鄉注力」課輔學伴計畫2020/02/012021/01/31272000教師研究計畫管理系統轉入之計畫
481082202003計畫主持人其他政府機關-其他政府單位109年度結合大專校院辦理就業服務補助計畫-外聘校園駐點職涯諮商2020/03/182020/10/3122503教師研究計畫管理系統轉入之計畫
491082202005計畫主持人其他政府機關-其他政府單位安心即時上工計畫2020/05/012021/06/305561586教師研究計畫管理系統轉入之計畫
501082202006計畫主持人教育部教育部補助協助大專校院學生因應嚴重特殊傳染病肺炎衝擊影響2020/06/092020/09/30272265教師研究計畫管理系統轉入之計畫
511091202008計畫主持人科技部探討硝酸甘油藉由降低胸腺嘧啶合成酶表現進而增加化療藥物順鉑與愛寧達毒殺人類非小細胞肺癌細胞的分子機轉2020/08/012021/07/31620000教師研究計畫管理系統轉入之計畫
521091202008共同主持人科技部探討硝化甘油透過AKT的失活與向下調控胸苷酸合酶表現在誘導人類非小細胞肺腺癌細胞毒性的角色 2020/08/012021/02/280
531091202101計畫主持人教育部110年教育優先區中小學生寒假營隊活動2021/01/012021/02/28240000教師研究計畫管理系統轉入之計畫
541091202101計畫主持人教育部110年度招收及輔導身心障礙學生工作計畫2021/01/012021/12/313839992教師研究計畫管理系統轉入之計畫
551091202101計畫主持人教育部109-110年度教育部補助大專校院推動健康促進學校實施計畫2021/01/012021/12/31200000教師研究計畫管理系統轉入之計畫
561091202101計畫主持人教育部110年度教育部補助大專校院聘用專兼任專業輔導人員計畫2021/01/012021/12/313586497教師研究計畫管理系統轉入之計畫
571091202101計畫主持人教育部青年發展署原力與你同在2021/01/012021/12/31270000教師研究計畫管理系統轉入之計畫
581092202104計畫主持人其他政府機關-其他政府單位110年度結合大專校院辦理就業服務補助計畫-外聘校園駐點職涯諮商2021/04/012021/10/3143685教師研究計畫管理系統轉入之計畫

獲獎榮譽(共計11筆)
序號學年度學期年度月份獲獎種類獲獎名稱頒獎單位
1098120099本校教學評量績優教師本校
2099120109本校『基礎分子生物學與實作之創新教材製作』優良社群本校
3099120109全國性大專校院獎勵特殊優秀人才獎勵科技部
4100120119全國性大專校院獎勵特殊優秀人才獎勵科技部
5100120119本校教學績優教師本校
6100120119本校教學評量績優教師本校
7101120129全國性大專院校實施特殊優秀人才教育部
8101120129全國性大專校院獎勵特殊優秀人才獎勵科技部
9101120129本校研究優良教師本校
10101120129本校教學績優教師本校
11102120139本校教學肯定獎本校

學術活動(共計13筆)
序號學年度學期年度月份活動分類活動名稱活動地點/期刊學報/比賽名稱
11051201611出席國際研討會105學年度第一學期第六屆國際植物化合物暨疾病預防與功能評估研討會 國立嘉義大學 
2104220165出席國際研討會The 6th International Congress on Chemical, Biological and Environmental Sciences (ICCBES 2016)日本 
31061201712出席研討會2017中國化學年會嘉義大學 
4105220174出席國際研討會5th International Conference on Chemical, Agricultural, Biological and Environmental Sciences (CAFES-17)日本 
5105220176出席研討會5th Taiwan International Symposium on Raman Spectroscopy (TISRS 2017) 嘉義大學 
6105220176其他TISRS 拉曼光譜年會嘉義大學 
7106120181出席研討會嘉大蛋白應用在水產養殖之成果發表會嘉義大學 
81071201811出席國際研討會107學年度第一學期參加3rd International Symposium of Biodiversity and Health in Southeast Asia嘉義大學 
91081201910其他108學年度第二學期擔任台灣生物科技暨健康產業協會 第一屆 學術推動委員會委員台灣生物科技暨健康產業協會 
101081201912出席國內研討會108學年度第二學期督辦彰雲嘉大學校院聯盟108年度教務交流活動活動嘉義大學 
11108120198出席國內研討會108學年度第二學期參加學術倫理研習3小時嘉義大學 
121091202008學術期刊論文審查109學年度第一學期擔任國防工業發展基金會委託研究審查委員國防工業發展基金會委託研究 
131091202010出席國際研討會2020生物科技暨健康產業國際學術研討會大會嘉義大學 
141091202010出席國際研討會109學年度第一學期擔任2020生物科技暨健康產業國際學術研討會大會籌備委員嘉義大學 

推廣工作(共計22筆)
序號學年度學期年度月份推廣類別推廣名稱推廣地點
11032201505學術演講或教學講習主講103學年度第二學期擔任國防發展基金會研究審查委員委員國防發展基金會 
21041201510學術演講或教學講習主講104學年度第一學期擔任PHYMED期刊文章審查國際期刊Phytomedicine 
31041201510學術演講或教學講習主講104學年度第一學期擔任JCRT期刊文章審查國際期刊Journal of Cancer Research and Therapeutics 
41041201512學術演講或教學講習主講104學年度第一學期擔任BCP期刊文章審查國際期刊Biochemical Pharmacology 
51041201512學術演講或教學講習主講104學年度第一學期擔任TUBI期刊文章審查國際期刊Tumor Biology 
61042201603其他104學年度第二學期科技部計畫審查 
71042201603其他國防發展基金會董事 
81042201607學術演講或教學講習主講104學年度第二學期嘉南藥理大學教師升等審查嘉南藥理大學 
91051201612其他105學年度第一學期擔任科技部南部科學工業園區管理局計畫審查 
101051201701學術演講或教學講習主講105學年度擔任中正大學教師評鑑委員會委員中正大學 
111052201702學術演講或教學講習主講105學年度第二學期陽明大學生物藥學所專題演講陽明大學生物藥學所 
121052201703其他105學年度第二學期科技部計畫審查 
131052201703其他擔任國防發展基金會董事 
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