研究成果列表
單位名稱微生物免疫與生物藥學系教師姓名吳進益
教師分級副教授專兼任專任
在校狀態專任行政職務微生物與免疫學系主任暨研究所所長

期刊論文（共計42筆）
序號學年度學期年度月份作者題目通訊作者作者順位期刊名稱卷數頁數關鍵字
1112120239I-Chen Lin, Jin-Yi Wu, Chuan-Yin Fang, Shou-Chie Wang, Yi-Wen Liu,* Shang-Tse Ho*Absorption and Metabolism of Urolithin A and Ellagic Acid in Mice and Their Cytotoxicity in Human Colorectal Cancer Cells否第二順位Evidence-Based Complementary and Alternative Medicine2023  8264716  
21111202212Jin-Yi Wu, Lih-Geeng Chen, Chia-Wen Hu, Kuan-Chi Chiu, Wenhsin Lin, Pei-Chun Ho, Brian Bor-Chun WengImmunotoxicity and Anti-Inflammatory Characterizations of Prenylated Flavonoids—The Lipophilic 7-O-Terpenylated Wogonin否第一順位Life12 2116  
3110220225C.-H. Shen, J.-Y. Wu, S.-C. Wang, C.-H. Wang, C.-T. Hong, P.-Y. Liu, S.-R. Wu, Y.-W. Liu*The suppressive role of phytochemical-induced glutathione S-transferase Mu 2 in human urothelial carcinoma cells否第二順位Biomedicine Pharmacotherapy 151 113102  
4110120219J-M Chang, J-Y Wu, S-H Chen, W-Y Chao, H-H Chuang, K-H Kam, P-W Zhao, Y-Z Li, Y-P Yen, Y-R Lee9-O-Terpenyl-Substituted Berberrubine Derivatives Suppress Tumor Migration and Increase Anti-Human Non-Small-Cell Lung Cancer Activity否第二順位International Journal of Molecular Sciences22 9864  
5109220212Ganbolor Jargalsaikhan, Jin-Yi Wu, Yen-Chou Chen, Ling-Ling Yang, Ming-Shun Wu*Comparison of the Phytochemical Properties, Antioxidant Activity and Cytotoxic Effect on HepG2 Cells in Mongolian and Taiwanese Rhubarb Species否第二順位Molecules26 1217  
6108220206JM Chang, KH Kam, WY Chao, PW Zhao, SH Chen, HC Chung, YZ Li, JY Wu*, YR Lee*Berberine Derivatives Suppress Cellular Proliferation and Tumorigenesis In Vitro in Human Non-Small-Cell Lung Cancer Cells是其他 International Journal of Molecular Sciences21 4218  
7108220205JIN-YI WU, EN-TUNG TSAI, FANG-YU YANG, JUI-FENG LIN, HUI-FEN LIAO, YU-JEN CHEN, CHENG-DENG KUOInhibition of Jurkat T Cell Growth by N-farnesyl-norcantharimide Through Up-regulation of Tumor Suppressor Genes and Down-regulation of Genes for Steroid Biosynthesis, Metabolic Pathways and Fatty Acid Metabolism否第一順位Anticancer Research40 2675-2685  
8108220202Lin,H.-J.; Ho,J.-H.; Tsai,L.-C.; Yang,F.-Y.; Yang,L.-L.; Kuo,C.-D.; Chen,L.-G.; Liu,Y.-W. Wu,J.-Y.*Synthesis and In Vitro Photocytotoxicity of 9-/13-Lipophilic Substituted Berberine Derivatives as Potential Anticancer Agents是其他Molecules25 677  
9107120191Ching-Chiung Wang, Hsyeh-Fang Chen, Jin-Yi Wu and Lih-Geeng Chen Stability of Principal Hydrolysable Tannins from Trapa taiwanensis Hulls否第三順位Molecules24 365  
10106120178Robin Y.-Y. Chiou*, Po-Chang Chiu, Ju-Chun Chang, Yu-Jang Li, Chia-Wen Hsieh, Jin-Yi Wu, et al.Discovery of New Stilbene Antioxidants of the Bio-Elicited Peanut Sprout Powder (BPSP) and Longevity Extension of Mice Fed with BPSP-Supplemented Diets否其他Food and Nutrition Sciences8 141-162  
11105120171C.-H. Lu, S.-H. Chen, Y.-S. Chang, Y.-W. Liu, J.-Y. Wu, Y.-P. Lim, H.-I Yu, Y.-R. Lee*Honokiol, a potential therapeutic agent, induces cell cycle arrest and program cell death in vitro and in vivo in human thyroid cancer cells否其他Pharmacological Research115 288-298  
12105120168MEI-YI LIN, SU-YIN CHIANG, YI-ZHEN LI, MEI-FANG CHEN, YUEH-SHENG CHEN, JIN-YI WU*,YI-WEN LIU*Anti-tumor effect of Radix Paeoniae Rubra extract on mice bladder tumors using intravesical therapy是其他ONCOLOGY LETTERS12 904-910  
13105120168Ming-Che Chang, Jin-Yi Wu, Hui-Fen Liao, Yu-Jen Chen, Cheng-Deng Kuo*Comparative assessment of therapeutic safety of norcantharidin, N-farnesyloxy-norcantharimide, and N-farnesyl-norcantharimide against Jurkat T cells relative to human normal lymphoblast: A quantitative pilot study否第二順位Medicine95 e4467  
14104120161HC Hsu, WM Chang, JY Wu, CC Huang, FJ Lu, YW Chuang, PJ Chang, KH Chen, et al. Folate deficiency triggered apoptosis of synoviocytes: role of overproduction of reactive oxygen species generated via NADPH oxidase/mitochondrial complex II and calcium perturbation否第三順位PLoS ONE11 e0146440  
151041201510SH Wang, CH Chen, CY Lo, JZ Feng, HJ Lin, PY Chang, LL Yang, LG Chen, YW Liu, CD Kuo, JY Wu*Synthesis and biological evaluation of novel 7-O-lipophilic substituted baicalein derivatives as potential anticancer agents是其他MedChemComm6 1864-1873  
16103220157Ming-Che Chang, Jin-Yi Wu, Hui-Fen Liao, Yu-Jen Chen and Cheng-Deng Kuo*N-farnesyloxy-norcantharimide inhibits progression of human leukemic Jurkat T cells through regulation of mitogen-activated protein kinase and interleukin-2 production否第二順位Anti-cancer Drugs26 1034-1042  
17103220157S.-H. Wang, C.-Y. Lo, Z.-H. Gwo, H.-J. Lin, L.-G. Chen, C.-D. Kuo and J.Y. Wu*Synthesis and Biological Evaluation of Lipophilic 1,4-Naphthoquinone Derivatives gainst Human Cancer Cell Lines是其他Molecules20 11994-12015  
18103220153Ming-Che Chang, En-Tung Tsai, Jin-Yi Wu, Hui-Fen Liao, Yu-Jen Chen and Cheng-Deng Kuo*N-Farnesyloxy-norcantharimide and N-farnesyl-norcantharimide inhibit the progression of leukemia and increase survival days in a syngeneic mouse leukemia model否第三順位Anti-cancer Drugs26 508-517  
19102220145Jin-Yi Wu*, Cheng-Deng Kuo, Chien-Yu Chu, Min-Shin Chen, Jia-Hua Lin, Yu-Jen Chen and HuSynthesis of Novel Lipophilic N-Substituted Norcantharimide Derivatives and Evaluation of Their Anticancer Activities是第一順位Molecules19 6911-6928  
20102220144Jen-Tsung Yang, Zih-Ling Li, Jin-Yi Wu, Fung-Jou Lu, Ching-Hsein Chen*, An oxidative stress mechanism of shikonin in human glioma 否第三順位PLoS ONE9 e94180  
21101220134Lee M.-Y., Liu Y.-W., Chen M.-H., Wu J.-Y., Ho H.-Y., Wang Q.-F., Chuang J.-J.Indirubin-3-monoxime promotes autophagic and apoptotic death in JM1 human acute lymphoblastic leukemia cells and K562 human chronic myelogenous leukemia cells否其他Oncol. Rep.29 2072-2078  
22101220134Wu J.-Y., Tsai K.-W., Li Y.-Z., Chang Y.-S., Lai Y.-C., Laio Y.-H., Wu J.-D., Liu Y.-W.*Anti-Bladder-Tumor Effect of Baicalein from Scutellaria baicalensis Georgi and Its Application In Vivo否第一順位Evid Based Complement Alternat Med2013 579751  
23101220133J.-Y. Wu, W.-C. Chen, Y.-Y. Wu, J.-T. Chen, L.-G. Chen, R. Y.-Y. Chiou*NMR-Based Elucidation of the Positional C6-O-Glucopyranosyl Substitution of Gomphrenin I Isolated from Basella alba Fruits 否第一順位Journal of Agricultural Science and Applications2 8-12  
24101120131Chih-Yu Lo, Lin-Chen Hsu, Min-Shin Chen, Yi-Jing Lin, Lih-Geeng Chen, Cheng-Deng Kuo, Jin-Yi Wu*Synthesis and anticancer activity of a novel series of 9-O-substituted berberine derivatives: a lipophilic substitute role是其他Bioorg. Med. Chem. Lett.23 305-309 berberine 
251011201210Shu-Mei Lin, Jin-Yi Wu, Chen Shu, Sophia Ferng, Chih-Yu Lo, Robin Y.-Y. Chiou*Identification and Mode of Action of 5‑Hydroxymethyl-2-furfural (5-HMF) and 1‑Methyl-1,2,3,4-tetrahydro- β-carboline-3-carboxylic Acid (MTCA) as Potent Xanthine Oxidase Inhibitors in Vinegars否第二順位J. Agric. Food Chem.60 9856-9862  
26099220113Shih-Hao Wang, Ming-Yuan Kao, She-Ching Wu, Dan-Yuan Lo, Jin-Yi Wu, Ju-Chun Chang, and R. Y.-Y ChiouOral Administration of Trapa taiwanensis Nakai Fruit Skin Extracts Conferring Hepatoprotection from CCl4-Caused Injury否其他J. Agric. Food Chem.59 3686-3692  
270991201012Jin-Yi Wu, Chi-Hung Chen, Wen-Huei Chang, King-Thom Chung, Yi-Wen Liu, Fung-Jou Lu, Ching-Hsein ChenAnti-cancer effects of protein extracts from Calvatia lilacina, Pleurotus ostreatus, and Volvariella volvacea是第一順位 Evidence-based Complementary and Alternative Medicine2011 ID 982368  
28098220105Cheng-Huang Shen, Jia-Jen Shee, Jin-Yi Wu, Yi-Wen Lin, Jiann-Der Wu, Yi-Wen Liu*Combretastatin A-4 inhibits cell growth and metastasis in bladder cancer cells and retards tumour growth in a murine orthotopic bladder tumour model否第三順位British Journal of Pharmacology160 2008-2027  
29098120101Mou-Tsy Chou, Wen-Cheng Chu, Wei-Fu Hong, Min-Cong Huang, Wen-Je Liu, Shin-Chang Lin, See-Chang Huan1,10-Phenanthroline stabilizes mRNA of the carcinogen-metabolizing enzyme, cytochrome P450 1a1否其他Toxicology Letters192 252-260  
30098120101Jin-Yi Wu, Kun-Wei Tsai, Jia-Jen Shee, Yi-Zhen Li, Ching-Hsein Chen, Jing-Jing Chuang, Yi-Wen Liu*4’-Chloro-3,5-dihydroxystilbene induces lung cancer cell death through multiple pathways否第一順位Acta Pharmacologica Sinica31  81‒92  
31097120091Yi-Chun Chen, Shi-Chuan Chang, Ming-Hsi Wu, Kai-An Chuang, Jin-Yi Wu, Wei-Jern Tsai, Yuh-Chi KuoNorcantharidin reduced cyclins and cytokines production in human peripheral blood mononuclear cell否其他Life Sciences84 218-226  
32096120081Wu, Jin-Yi; Chung, King-Thom; Liu, Yi-Wen; Lu, Fung-Jou; Tsai, Ruei-Shiun; Chen, Chi-Hung; Chen, ChiSynthesis and Biological Evaluation of Novel C(6) Modified Baicalein Derivatives as Antioxidative Agents否第一順位Journal of Agricultural and Food Chemistry56 2838-2845  
33092120041Huang, K.-H., Wu, J.-Y., Wu, W.-S., Chang, C.-C., Lee, H.-L., Chang, T.-C.Laser-induced hole filling by energy transfer between chromophores bound to DNA是第二順位J. Luminescence107 213-219  
34091120031Chang, C.-C., Wu, J.-Y., Chien, C.-W., Wu, W.-S., Liu, H., Kang, C.-C., Yu, L.-J., Chang, T.-C.A Novel Fluorescence Carbazole Derivative for Recognizing Specific Quadruplex Structures是第二順位Anal. Chem.75 6177-6183  
35091120031Chang, C.-C., Wu, J.-Y., Chang, T.-C.A carbazole Derivative Synthesis for Stabilizing the Quadruplex Structure是第二順位J. Chin. Chem. Soc.50 185-188  
36091120031Wu, J.-Y., Chang, C.-C., Yan, C.-S., Chen, K.-Y., Kuo, I.-C., Mou, C.-Y., Chang, T.-C.Structural Isomers and Binding Sites of Guanine-rich Quadruplexes investigated by Induced Circular Dichroism of Thionin: Loops and Tails是第一順位J. Biomol. Struct. Dyn.21 135-140  
37090120021Wu, J.-Y., Chang, C.-C., Yang, Y.-P., Chang, T.-C., ”Investigation of Guanine-rich Quadruplex StructInvestigation of Guanine-rich Quadruplex Structures by Thionin否第一順位Biophys. J.82 152A  
38090120021Yang, Y.-P., Wu, J.-Y., Chang, C.-C., Yan, C.-S., Chang, T.-C.Energy Transfer Dynamics of Thionin Investigated by Broad Non-resonant Holes是第二順位J. Luminescence98 257-263  
39088120001Ho, T.-I., Ho, J.-H., Wu, J.-Y.Novel Acid-Catalyzed Hydrolysis of an Intermediate from a Photorearrangement of Stilbenes否第三順位 J. Am. Chem. Soc.122 8575-8576  
40088119999Ho, T.-I.,* Wu, J.-Y., Wang, S.-L.Novel Photochemical Rearrangement of Styrylfurans否第二順位Angew. Chem. Int. Ed38 2558-2560  
41087219996Wu, J.-Y., Ho, J.-H., Shin, S.-M., Hsieh, T.-L., Ho, T.-I.,*Solvent-Dependent Photochemical Rearrangements of Ethers of Styrylheterocycles否第一順位Organic Letters1 1039‒1041  
420871199810Wu, J.-Y., Mai, J.-C., Pan, K., Ho, T.-I.,*Reverse Regioselective Photosensitized Nucleophilic Addition of Arylcyclopropanes否第一順位Tetrahedron Letters39 647‒650  

會議論文（共計42筆）
序號學年度學期年度月份作者題目通訊作者作者順位發表性質會議論文集或研討會名稱地點
1112220243Cheng-You Haung (黃丞佑), Jin-Yi Wu (吳進益)Synthesis and photocytotoxic activities of novel berberine-cyproheptadine derivatives as potential anticancer agent是第二順位壁報發表The 38th Joint Annual Conference of Biomedical Science 國防醫學院 
2111220233Jing-Ru Su (蘇敬茹), Ya-Lan Syu (許雅嵐), Cheng-You Haung (黃丞佑), Jin-Yi Wu (吳進益)Photocytotoxic Effects of Synthetic Cycloberberine Derivatives on Human Colorectal Cancer Cells是其他壁報發表The 37th Joint Annual Conference of Biomedical Science 國防醫學院 
3110220223Meng-Ji Li (李孟輯), Jing-Ru Su (蘇敬茹), Jin-Yi Wu (吳進益)Synthesis and photocytotoxicity of 9-O-lipophilic and 12-N/heterocyclic substituted berberine derivatives as potential anticancer agents是第三順位壁報發表The 36th Joint Annual Conference of Biomedical Science  
4107220193Hui-Chien Hsu, Po-Jung Huang, Yi-Han Chen, Ting-Fang Lai, Ya-Lun Chan,Jin-Yi WuSynthesis of a series of lipophilic substituted 1,4-naphthoquinone derivatives and evaluated for their anticancer activity是其他壁報發表The 34th Joint Annual Conference of Biomedical Science Taipei, Taiwan 
5106220183Fang-Yu Yang (楊芳俞), Hui-Chien Hsu, Zhong-Jie Lian, Yi-Han Chen, Hong-Jhih Lin, Jin-Yi Wu (吳進益)Synthesis and photocytotoxicity of 13-O-lipophilic substituted berberine derivatives against human colon cancer cells是其他壁報發表 The 33th Joint Annual Conference of Biomedical Science Taipei, Taiwan 
6105220173Fang-Yu Yang (楊芳俞), Hong-Jhih Lin (林鴻志), Jou-Man Huang (黃柔嫚), Jin-Yi Wu (吳進益)*Synthesis and photocytotoxicity of 9-/13-lipophilic substituted berberine derivatives and evaluated for their anticancer activity是其他壁報發表The 32th Joint Annual Conference of Biomedical Science Taipei, Taiwan 
71051201612Yu-Xin Chen (陳昱心), Jou-Man Huang (黃柔嫚), Chia-Wei Hsu (許家瑋), Wei-Te Su (蘇偉德), Jin-Yi Wu (吳進益)*Synthesis, biological evaluation and their interactions with human serum albumin of 9-lipophilic berberine derivatives as potential anticancer agents是其他書面發表中國化學會105年會, 台灣台中  
8104220163林鴻志, 蔡立宸, 黃柔嫚, 吳進益*Synthesis, cellular uptake and photocytotoxicity of 9-/13-lipophilic berberine derivatives as potential anticancer agents是其他書面發表The 31th Joint Annual Conference of Biomedical Science, Taipei, Taiwan  
9103220153Jia-Hua Lin, Nian-Ping Wu, Li-Chan Chang and Jin-Yi WuSynthesis of Novel Ring-Opened Norcantharimide Derivatives and Biological Evaluation for Their Anticancer Activities Compared With Ring-Closed Derivatives是其他書面發表The 30th Joint Annual Conference of Biomedical Science, Taipei, Taiwan  
101031201411Hong-Jhih Lin (林鴻志), Min-Shin Chen (陳珉新), Li-Chen Tsai (蔡立宸), Chia-Wei Hsu (許家瑋), Jin-Yi Wu (吳進益)Synthesis of novel 9-/13-lipophilic substituted berberine derivatives and evaluated for their anticancer activity是其他書面發表中國化學會103年會, 台灣新竹  
11102220143Ji-Zhen Feng, Jian-Zhong Wang, Bo-Ya Jhang, Ya-Fang Hou, Yi-Wen Liu, Jin-Yi WuSynthesis of New Lipophilic Substituent Baicalein Derivatives and Biological Evaluation as Potent Antitumor Agents是其他書面發表The 29th Joint Annual Conference of Biomedical Science, Taipei, Taiwan  
12102220143Jin-Yi Wu (吳進益), Wen-Lee Liang (梁文俐), Bor-Chun Weng (翁博群), Jin-Chuan Tsai (蔡金川), Fei-Peng Lee (李飛鵬),Drug Interaction with Warfarin of the Top Hundred Chinese Medicinal Prescriptions in Taiwan否第一順位書面發表The 29th Joint Annual Conference of Biomedical Science, Taipei, Taiwan  
13102220143Jin-Yi Wu (吳進益), Bor-Chun Weng (翁博群), Wen-Lee Liang (梁文俐), Fei-Peng Lee (李飛鵬), Ling-Ling Yang (楊玲玲)Pain Reduction Effects of Ibuprofen and Integrative Chinese Medicinal Prescription-Jia-Wei-Siao-Yiao-San in Mice否第一順位書面發表 The 29th Joint Annual Conference of Biomedical Science, Taipei, Taiwan  
14102220143Wei-Chih Chen, Ming-Shun Wu, Bor-Chun Weng, Jin-Yi Wu, Fei-Peing Lee, Chih-Hsiung Wu, Ling-Ling YangIn Vivo Hepatic and Renal Protective Capability of Ampelopsis cantonensis Extract against Oxidative Stress Induced by Carbon Tetrachloride否其他書面發表The 29th Joint Annual Conference of Biomedical Science, Taipei, Taiwan  
151021201310Min-Shin Chen, Hong-Jhih Lin, Pei-Ru Cai, and Jin-Yi Wu*Synthesis and biological evaluation of a series of 9-O-/9-N-lipophilic substituted berberine derivatives as potential anticancer agents是其他壁報發表 9th AFMC International Medicinal Chemistry Symposium The Grand Hotel, Taipei 
16101220133Wei-Chih Chen (陳瑋智)、Jin-Yi Wu (吳進益)、Ling-Ling Yang (楊玲玲)Comparison extraction solvents on inhibitory effects of free radical and lipid peroxidation on rat kidney/liver mitochondria of Ampelopsis cantonensis root and resveratrol是第一順位書面發表The 28th Joint Annual Conference of Biomedical Science Taipei, Taiwan 
17101220133Min-Shin Chen(陳珉新), Pei-Ru Cai (蔡佩茹), Ya-Ru Yang(楊雅如), Lih-Geeng Chen(陳立耿), Jin-Yi Wu (吳進益)Synthesis and cytotoxicity activity of newly 9-O-substituted lipophilic berberine derivatives是第一順位書面發表The 28th Joint Annual Conference of Biomedical Science Taipei, Taiwan 
181011201212Min-Shin Chen (陳珉新), Yi-Jing Lin (林宜靜), Lih-Geeng Chen (陳立耿), Jin-Yi Wu (吳進益)Synthesis and biological evaluation of a novel series of 9-O-substituted lipophilic berberine derivatives as anti-cancer agents是其他書面發表中國化學會101年會  台灣台南 
19100220123Zhong-Heng Gwo (郭仲恒), Chih-Kuo Huang (黃治國), Ji-Zhen Feng(馮吉振), Shao-Hung Wang (王紹鴻), Jin-Yi Wu (吳進益)Synthesis of 1,4-naphthoquinone derivatives and biological activity as antitumor agents是其他書面發表The 27th Joint Annual Conference of Biomedical Science  
201001201112Po-Tsun Lai, Zhong-Heng Gwo, Yi-Jing Lin, Lih-Geeng Chen, Jin-Yi Wu*Synthesis and biological evaluation of a series of coumarin derivatives as anti-leukemia agents是其他書面發表中國化學會100年會 台灣新竹 
21099220113Chien-Yu Chu, Cheng-Deng Kuo, Jin-Yi Wu＊Synthesis and biological evaluation of a new series of norcantharidin analogues as antitumor agents是第三順位書面發表The 26th Joint Annual Conference of Biomedical Science  
22099220113Pei-Hsun Tsai, Yi-Wen Liu, Jin-Yi Wu＊Synthesis and anticancer activity of novel chloride-substituted stilbenes是第三順位書面發表The 26th Joint Annual Conference of Biomedical Science  
23098220103Wang Hsiang-Ching (王湘晴), Chen Yu-Hsin (陳昱欣), 邱千玳 (Cian-Dai Ciou), Lai Po-Tsun (賴柏村), Chen Ching-HseiSynthesis and Biological Evaluation of Novel C(8) Modified Wogonin Derivatives as Anticancer Agents是第一順位書面發表The 25th Joint Annual Conference of Biomedical Science Taipei, Taiwan 
240981200912林士弘、褚倩諭、蔡佩洵、劉怡文、吳進益Synthesis and biological evaluation of novel series resveratrol analogues as potent anticancer agents是第一順位書面發表中國化學會98年會 台灣高雄 
25097220093Chin-Hsiang Chang, Shih-Hung Lin, Jin-Yi Wu*Synthesis and Biological Evaluation of Novel Series Chalcone Analogues as Anti-tumor Agents是第一順位書面發表The 24th Joint Annual Conference of Biomedical Science Taipei, Taiwan 
26097220093Yi-Zhen Li, Jin-Yi Wu, Kun-Wei Tasi, Yi-Wen Liu*Mechanism study of Resveratrol analogue 4-Chloro-3,5-dihydroxystilbene-induced Cell Death in Human Lung Carcinoma Cells是第一順位書面發表The 24th Joint Annual Conference of Biomedical Science Taipei, Taiwan 
270971200812傅士軒、張至翔、吳進益Synthesis and Biological Evaluation of Norcantharidin Analogues as Protein Phosphatase Inhibitor是第一順位書面發表中國化學會97年會 台灣彰化 
28096220083Shing-Rown Wu, Jin-Yi Wu＊, and Yi-Wen Liu＊Synthesis and Biological Evaluation of Novel Series Combretastatin A-4 Analogues as Potent Antitubulin Agent是第一順位書面發表二十三屆生醫年會 台北, 國防醫學院 
290961200712Yu-Hsin Chen (陳昱欣), Ruei-Shiun Tsai (蔡睿勳) , Ching-Hsein Chen(陳俊憲) and Jin-Yi Wu (吳進益)* Synthesis and Biological Evaluation of Novel Baicalein Derivatives as Antioxidative Agents 是第一順位書面發表96年度中國化學會年會 臺灣, 新竹 
30095220073Ruei-Shiun Tsai (蔡睿勳), Yan-Zhi Liu (劉諺至), Weng, Bor-Chun Brian (翁博群)and Jin-Yi Wu (吳進益)*Synthesis, Investigation on Immunity and Antioxidative Activities of Novel Flavonoid Derivatives是第一順位書面發表二十二屆生醫年會 台北,國防醫學院 
310951200611Arethusa Ko (柯昭宇) , Yi-Wen Liu (劉怡文) and Jin-Yi Wu (吳進益)*Synthesis of Resveratrol and Analogues as Potential Antioxidant and Anticancer Agents是第一順位書面發表95年度中國化學會年會 臺灣, 台中 
32094220063Bor-Chun Weng, Jin-Yi WuSynthesis, Investigation on Immunity and Cancer Prevention of Wogonin Derivatives是第一順位書面發表Experimental Biology 2006 San Francisco, California 
330941200512Bor-Chun Weng and Jin-Yi Wu*Synthesis, Investigation on Immunity and Cancer Prevention of Wogonin Derivatives是第一順位書面發表植物化合物國際研討會symposium on phytochemicals: bioactivity, genomics, and proteomics 國立嘉義大學蘭潭校區國際會議廳 
340941200511吳進益*、劉諺至、蔡鐘寬、柯昭宇合成新的wogonin衍生物對抗氧化性及免疫細胞增生在結構與活性關係之研究是第一順位書面發表94學年中國化學年會 中山大學/高雄市 
35090120021C.-C. Chang, J.-Y. Wu, T.-C. ChangThionin Interacting with Guanine-rich Hairpin Duplexes and Quadruplexes否第二順位書面發表中國化學會91年會 台北 
36090120021C.-C. Chang, J.-Y. Wu, T.-C. ChangThionin Interacting with Guanine-rich Hairpin Duplexes and Quadruplexes否第二順位書面發表中國化學會91年會 台北 
37090120021C.-C. Chang, K.-Y. Chen, Y.-C. Kuo, J.-Y. Wu, T.-C. ChangConversion between Waston-Crick and Hoogsteen Hydrogen Bonding of Guanine-rich DNA否其他書面發表中國化學會91年會 台北 
38090120021J.-Y. Wu, H. Liu, C.-J. Koun, C.-C. Chang, J.-J. Lin, T.-C. ChangInvestigation of tricyclic aromatic molecules for antitumour drug design否第一順位書面發表中國化學會91年會 台北 
39090120021J.-Y. Wu, C.-C. Chang, C.-S. Yan, Y.-P. Yang, C.-Y. Mou, T.-C. ChangCircular Dichroism Study of Guanine-rich Quadruplexes Recognized by Thionin: Loops and Tails否第一順位書面發表中國化學會91年會 台北 
40090120021J.-Y. Wu, C.-C. Chang, Y.-P. Yang, T.-C. ChangInvestigation of Guanine-rich Quadruplex Structures by Thionin否第一順位書面發表The 46th Annual Meeting Biophysical Society San Francisco 
41089120011Yih-Pey Yang, Jin-Yi Wu, Cheng-Chung Chang, Ta-Chau ChangInvestigation of thionin and its complexes with guanine-rich DNA by satellite hole spectroscopy否第二順位書面發表7th international Meeting on Hole Burning, Single Molecule, and Related Spectroscopies: Science and  Taipei, Taiwan 
42089120011吳進益, 張健忠, 張大釗Thionin對含G鹼基四股異構物隻認知機制: CD光譜研究否第一順位書面發表中國化學會90年會 台南 

專書著作（共計2筆）
序號學年度學期年度月份作者書名出版社國際標準書號
10991201010吳進益，邱義源夢幻香水 野薑花的春天科學月刊 9864174452 
2091120031張大釗，張健忠，吳進益光譜研究Thionin-DNA端粒的作用與端粒穩定藥物的研發科儀新知 

研究計畫（共計46筆）
備註欄說明：「教師研究計畫管理系統轉入之計畫」（係指依「國立嘉義大學產學合作計畫實施要點」第3點規定，與政府機關、法人、公民營事業機構、民間團體、學術研究機構等合作辦理有關事項，以本校名義與合作機構辦理簽約，其經費撥入本校之產學合作計畫。)
序號學年度學期年度月份參與性質委辦單位計畫名稱開始日期結束日期經費備註欄
11141202512計畫主持人其他民間企業團體-其他民間企業團體或個人合成新型三種抗組織胺-羥肟酸衍生物作為抗癌藥物之研究2025/12/012026/11/30500,000教師研究計畫管理系統轉入之計畫
2113220257計畫主持人國家科學及技術委員會大專學生研究計畫大專生計畫：Synthesis and biological evaluation of curcumin and its derivatives bearing with boron trifluoride against human cancer cell lines (合成薑黃素及其衍生物接合三氟化硼及評估其抗癌活性之研究)（指導學生：黃興弘）2025/07/012026/02/2858,000教師研究計畫管理系統轉入之計畫
3113220257計畫主持人國家科學及技術委員會大專學生研究計畫大專生計畫：合成新型9-O-小檗鹼接合地氯雷他定作為潛在光毒性抗癌藥物之研究 Synthesis and photocytotoxic activity of novel 9-O- berberine-desloratadine conjugated containing n-alkyl or PEG linker as potential anticancer agent（指導學生：陳盈穎）2025/07/012026/02/2848,000教師研究計畫管理系統轉入之計畫
41131202411計畫主持人其他民間企業團體-其他民間企業團體或個人合成新型Cyproheptadine及Desloratadine衍生物作為抗肝癌藥物之研究2024/11/152025/11/14600,000教師研究計畫管理系統轉入之計畫
5112220247計畫主持人其他民間企業團體-其他民間企業團體或個人合成新型Cyproheptadine-及Desloratadine-Vorinostat衍生物作為抗癌活性之研究2024/07/012025/06/30380,000教師研究計畫管理系統轉入之計畫
6111220237計畫主持人國家科學及技術委員會大專學生研究計畫大專生計畫：合成新型小檗鹼-佩你安衍生物作為潛在的光毒性抗癌藥物之研究－指導學生：黃丞佑2023/07/012024/02/2948,000教師研究計畫管理系統轉入之計畫
7111120231計畫主持人其他民間企業團體-其他民間企業團體或個人生命科學院附設檢驗中心-NMR檢驗室2023/01/012023/12/31142,600
8110120221計畫主持人其他民間企業團體-其他民間企業團體或個人以PROTAC技術設計及合成Cyproheptadine -Vorinostat及-Thalidomide藥物作為抗癌活性之研究2022/01/012023/12/311,500,000教師研究計畫管理系統轉入之計畫
9109120208計畫主持人其他民間企業團體-其他民間企業團體或個人雲林在地土肉桂產品開發及精油應用2020/08/012021/01/31250,000教師研究計畫管理系統轉入之計畫
10108120201計畫主持人其他民間企業團體或個人生命科學院附設檢驗中心-NMR檢驗室2020/01/012020/12/31316,000
111081201912計畫主持人國家科學及技術委員會108年度 國立嘉義大學自有貴重儀器共同使用服務計畫2019/12/012020/12/31493,000
121081201910計畫主持人其他民間企業團體-其他民間企業團體或個人台灣丹參栽培及主成分生物活性分析探討2019/10/012020/03/31250,000
13107120191計畫主持人其他民間企業團體或個人生命科學院附設檢驗中心-NMR檢驗室2019/01/012019/12/31316,000
141071201812計畫主持人其他民間企業團體-其他民間企業團體或個人台灣丹參萃取及主成分定量分析探討2018/12/012019/05/31250,000
151071201812計畫主持人國家科學及技術委員會國立嘉義大學自有貴重儀器共同使用服務計畫2018/12/012019/12/31297,000
16106120181計畫主持人其他民間企業團體或個人 生命科學院附設檢驗中心-NMR檢驗室2018/01/012018/12/31316,000
17105120169計畫主持人其他民間企業團體-其他民間企業團體或個人鮮魚精萃取技術之探討2016/09/152016/12/14326,238
18103120151國科會其他政府機關-其他政府單位新型的親脂性取代去甲斑蝥素衍生物之合成、抗癌活性及藥物動力學評估2015/01/012015/12/31260,000
19103120151計畫主持人其他政府基金(如國立大學)生命科學院附設檢驗中心-檢驗室2015/01/012015/12/31316,000
201031201411計畫主持人國家科學及技術委員會國立嘉義大學自有貴重儀器共同使用服務計畫2014/11/012015/12/31327,000
21102120141計畫主持人校內行政及教學單位生命科學院附設檢驗中心-食品檢驗室2014/01/012014/12/31316,000
22102120141計畫主持人其他民間企業團體-其他民間企業團體或個人夜來香精油萃取技術開發及成分鑑定品管建立2014/01/012014/12/31316,000
23102120141計畫主持人其他政府機關-其他政府基金(如國立大學)新型的親脂性取代去甲斑蝥素衍生物之合成及其抗癌活性評估2014/01/012014/12/31220,000
24101220137計畫主持人其他政府機關-其他政府單位102年補助大專校院辦理就業學程計畫-生技製藥培育人才學程2013/07/012014/08/31750,000
25101120131計畫主持人其他政府機關-其他政府基金(如國立大學)生命科學院附設檢驗中心-食品檢驗室2013/01/012013/12/31316,500
26100220127共同主持人國家科學及技術委員會政策導向計畫:低碳臺灣行動車巡迴體驗活動之推廣與研究2012/07/312013/10/312,500,000
27100120121計畫主持人其他政府機關-其他政府基金(如國立大學)生命科學院附設檢驗中心-食品檢驗室2012/01/012012/12/31207,000
28100120121國科會其他政府機關-其他政府單位去甲基斑蝥醯胺衍生物合成及抗癌活性之評估2012/01/012012/12/31368,000
29100120118共同主持人國家科學及技術委員會「低碳臺灣．高瞻未來」行動博物館－節能減碳行動巡迴體驗活動之推廣與研究2011/08/012012/06/302,588,000
30099120111計畫主持人校級附屬單位及中心(自營)生命科學院附設檢驗中心-食品檢驗室2011/01/012011/12/3189,950
31098120101總計畫主持人農業部農糧署去甲基斑蝥醯胺衍生物合成及蛋白質磷酸分解酶抑制和抗癌活性之評估2010/01/012011/01/01500,000
32098120101總計畫主持人其他合作單位去甲基斑蝥醯胺衍生物合成及蛋白質磷酸分解酶抑制和抗 癌活性之評估2010/01/012011/01/01500,000
33098120098總計畫主持人其他民間企業團體-其他基金(如基金會)黃酮類驗生物合成與抗氧化和抗菌活性評估2009/08/012010/07/31316,800
34097120091計畫主持人其他政府機關-其他政府基金(如國立大學)去甲基斑蝥素衍生物合成及蛋白質磷酸酶抑制活性之評估2009/01/012010/01/01670,000
35096120081總計畫主持人其他合作單位新型去甲基斑蝥素衍生物合成及抗癌活性之新藥開發評估2008/01/012009/01/01900,000
36096120078計畫主持人國家科學及技術委員會合成二苯乙烯衍生物在抗氧化及抗癌藥物之研究2007/08/012008/07/31688,000
37095220073國科會校級附屬單位及中心(自營)黃芩有效成分及其洐生物的生物活性評估、納豆激酶活性檢測實驗室之建構-整合型計畫2007/03/012007/12/31400,000
38095120071總計畫主持人其他合作單位去甲基斑蝥素衍生物合成及蛋白質磷酸抑制活性之評估2007/01/012008/01/01670,000
39095120071計畫主持人其他合作單位設計及合成新型具有抗癌藥物的Norcantharidin衍生物2007/01/012007/12/31700,000
40095120068計畫主持人國家科學及技術委員會合成新的黃酮類衍生物在免疫及癌症預防藥物之研究2006/08/012007/07/31685,000
41094220063計畫主持人校級附屬單位及中心(自營)利用生物活性分析平台評估忍冬(金銀花 Lonicera japonica)、 穗花蛇菰(Balanophora laxiflora)和馬尼拉欖仁(Terminalia calamasana)多酚類在醫療及保護之功用 2006/03/012006/12/31200,000
42094120058計畫主持人國家科學及技術委員會合成新的具有抗氧化及抗癌藥物的黃酮類衍生物2005/08/012006/07/31667,000
43093220056計畫主持人校級附屬單位及中心(自營)增購檢驗分析及技術推廣服務中心儀器費2005/06/012006/05/311,200,000
44093220056計畫主持人校級附屬單位及中心(自營)建構生物活性成分高效分離純化及活性檢測之技術平台2005/06/012006/05/315,600,000
45093120051計畫主持人農業部無患子高附加價值生物活性成分之分離與應用2005/01/012007/12/311,359,000
46092220043計畫主持人校級附屬單位及中心(自營)中草藥及保健食品成分及毒物分析實驗室2004/03/312005/03/301,870,000

專利（共計6筆）
序號學年度學期年度月份專利分類申請國專利種類專利名稱字號開始日期結束日期金額
11071201812國內中華民國發明一種包含天然二苯乙烯化合物之醫藥組合物及該化合物之用途發明專利第I 644668號2018/12/212034/10/020
2105220173國內中華民國發明新穎親脂性之N-取代去甲基斑蝥素衍生物及其用途發明專利第I 573589號2017/03/112034/11/200
3104220165國際USA發明Cheng-Deng Kuo, Taipei (YW); Yu-Jen Chen, Taipei (TW); Jin-Yi Wu, Chiayi (TW); Hui-Fen Liao, Chiayi (TW) “NOVEL LIPOPHILIC N-SUBSTITUTED NORCANTHARIMIDE DERIVATIVES AND USES THEREOF"US20160145264A12016/05/262046/05/250
4103220156國內中華民國　發明羅至佑 (TW) LO, CHIH YU；陳侶螢 (TW) CHEN, LU YING；林淑美 (TW) LIN, SHU MEI；吳進益 (TW) WU, JIN YI "月桃萃取物及其用途與萃取方法"I5117362015/06/012030/05/300
5103220152國內中華民國發明陳裕仁、郭正典、吳進益、廖慧芬，”去甲基斑蝥酸二鈉於調控人類樹突細胞之用途”中華民國發明專利第I 472326號2015/02/112033/04/220
6093220054國際USA發明Recognition specific quadruplex structures by a novel fluorescence carbazole derivative 10/690,984.2003/10/222013/10/210

獲獎榮譽（共計2筆）
序號學年度學期年度月份獲獎種類獲獎名稱頒獎單位
11081201912全國性國家新創獎 新創精進獎/利用本土生物資材調製高級夢幻香水之研發其他
2098220105全國性 第七屆國家新創獎 利用本土生物資材調配高級夢幻香水之研發教育部

學術活動（共計57筆）
序號學年度學期年度月份活動分類活動名稱活動地點/期刊學報/比賽名稱
1112220243出席國內研討會38生物醫學聯合學術年會國防醫學院 
2112220242學術期刊論文審查HERMED-D-23-01742_reviewerJournal of Herbal Medicine 
3112120238出席國內研討會2023第27屆細菌學研討會嘉義市 
4111220236學術期刊論文審查ijms-2474351-peer-review-v1International Journal of Molecular Sciences 
5111220233出席國際研討會37生物醫學聯合學術年會國防醫學院 
6111120231學術期刊論文審查pharmaceutics-2120825-peer-review-v1Pharmaceutics 
71111202211學術期刊論文審查SUSCP-D-22-00839_reviewerSustainable Chemistry and Pharmacy 
8111120229學術期刊論文審查catalysts-1907945Catalysts 
9110220226學術期刊論文審查molecules-1797221-peer-review-v1Molecules 
10110220224學術期刊論文審查BIOPHA-D-22-01391Biomedicine Pharmacotherapy 
11110220222學術期刊論文審查molecules-1610847-peer-review-v1Molecules 
12110120218學術期刊論文審查BIOPHA-D-21-02501 Biomedicine Pharmacotherapy 
13109220217學術期刊論文審查ijms-1283714-peer-review-v1International Journal of Molecular Sciences 
14109220217學術期刊論文審查MCRE-D-21-00452Medicinal Chemistry Research 
15109220215學術期刊論文審查pharmaceutics-1231363-peer-review-v1Pharmaceutics 
16109220214學術期刊論文審查antioxidants-1178401-peer-review-v1Antioxidants 
17109120211學術期刊論文審查processes-1095890-peer-review-v1Processes 
181091202012學術期刊論文審查molecules-1047757-peer-review-v1Molecules 
19108220203學術期刊論文審查學術期刊論文審查-molecules-739216Molecules 
20108120201學術期刊論文審查學術期刊論文審查-Journal of Ethnopharmacology JEP_2019_4882_Original_V1Journal of Ethnopharmacology 
211081201911學術期刊論文審查學術期刊論文審查-Journal of Pharmacy and Pharmacology, Manuscript Number: JPP-19-0895Journal of Pharmacy and Pharmacology 
221081201910學術期刊論文審查Manuscript ID: molecules-625774Molecules 
23108120199學術期刊論文審查期刊論文審查Medicinal Chemistry Research-MCRE-D-19-00556Medicinal Chemistry Research 
24107220194學術期刊論文審查學術期刊論文審查-molecules-482276Molecules 
25107120189學術期刊論文審查學術期刊論文審查Medicinal Chemistry Research MCRE-D-18-00591Medicinal Chemistry Research 
26107120188學術期刊論文審查JEP_2018_2402Journal of Ethnopharmacology 
27106220187學術期刊論文審查Manuscript ID: molecules-326132Molecules 
28106220187學術期刊論文審查Manuscript ID: molecules-326132Molecules 
29106220187學術期刊論文審查MCRE-D-17-00375Medicinal Chemistry Research 
30106220185學術期刊論文審查molecules-299941Molecules 
31106220183學術期刊論文審查BIOORG_2018_127Bioorganic Chemistry 
32106220182學術期刊論文審查Manuscript ID: molecules-272053Molecules 
331061201712學術期刊論文審查Manuscript ID: molecules-259382Molecules 
341061201710學術期刊論文審查Manuscript number: cmdc.201700625ChemMedChem 
35106120179學術期刊論文審查Manuscript ID: molecules-226818Molecules 
36106120178學術期刊論文審查NJ-ART-07-201 7-002531New Journal of Chemistry 
37105220172學術期刊論文審查Current Pharmaceutical Design, Manuscript Number: BSP-CPD-2017-1055Current Pharmaceutical Design 
381051201612學術期刊論文審查ACS Medicinal Chemistry Letters, Manuscript Number ID: ml-2016-00466tACS Medicinal Chemistry Letters 
391051201612學術期刊論文審查Chemical Biology Drug Design期刊論文審查Chemical Biology Drug Design 
401051201611學術期刊論文審查Molecules期刊論文審查, 審查號碼: molecules-126874Molecules 
411051201611學術期刊論文審查Medicinal Chemistry Research, Manuscript Number: MCRE-D-16-00731Medicinal Chemistry Research 
421051201610學術期刊論文審查Molecules期刊論文審查Molecules 
43105120169學術期刊論文審查Molecules期刊論文審查Molecules 
44105120168學術期刊論文審查Molecules期刊論文審查Molecules 
45104220167學術期刊論文審查International Journal of Molecular Sciences, Manuscript Number: ijms-139617International Journal of Molecular Sciences 
46104220166學術期刊論文審查Bioorganic Medicinal Chemistry Letters, Manuscript Number: BMCL-D-16-00960Bioorganic Medicinal Chemistry Letters 
47104220164學術期刊論文審查Molecules期刊論文審查, 審查號碼: molecules-126874Molecules 
481041201512學術期刊論文審查MedChemComm, MD-RES-12-2015-000577MedChemComm 
491041201511學術期刊論文審查Manuscript ID: molecules-105713Molecules 
50103220157學術期刊論文審查Journal of the Serbian Chemical Society期刊論文審查Journal of the Serbian Chemical Society 
51103220156學術期刊論文審查Research on Chemical Intermediates, Manuscript Number: RINT-D-15-00502Research on Chemical Intermediates 
52103220154學術期刊論文審查PLoS One, Manuscript Number: PONE-D-15-10496PLoS One 
53103220154學術期刊論文審查Bioorganic Medicinal Chemistry Letters, Manuscript Number: BMCL-D-15-00461Bioorganic Medicinal Chemistry Letters 
54103220153學術期刊論文審查Research on Chemical Intermediates, Manuscript Number: RINT-D-14-01056Research on Chemical Intermediates 
551031201410學術期刊論文審查Medicinal Chemistry Research, Manuscript Number: MCRE-D-14-00936R1Medicinal Chemistry Research 
56101220136學術期刊論文審查Letters in Drug Design Discovery期刊論文審查Letters in Drug Design Discovery 
571011201212學術期刊論文審查Bioorganic Medicinal Chemistry Letters, Manuscript ID: BMCL-D-12-02278Bioorganic Medicinal Chemistry Letters 

推廣工作（共計32筆）
序號學年度學期年度月份推廣類別推廣名稱推廣地點
11121202311輔導校內碩士班口試委員 
2110120221輔導校內碩士在職專班口試委員 
3110120221其他校內碩士班口試委員嘉義市 
4109220217輔導校內碩士班口試委員 
5109220217學術演講或教學講習主講擔任110學年第一學期"微生物於新興跨域食品生技加值技術之應用趨勢"授課師資國立嘉義大學 
6109220216輔導校外碩士班口試委員臺北市 
7109220214學術演講或教學講習主講嘉義市國立嘉義大學校友會-第十三屆秘書組長嘉義市國立嘉義大學校友會 
81091202010學術演講或教學講習主講協助-山海希望工程計畫-教師講習活動嘉義縣黎明國小 
91091202010學術演講或教學講習主講2020生物科技暨健康產業國際學術研討會-研習證明書國立嘉義大學/台灣生物科技暨健康產業學會 
101091202010學術演講或教學講習主講擔任2020生物科技暨健康產業國際學術研討會-評審委員國立嘉義大學/台灣生物科技暨健康產業學會 
11109120209學術演講或教學講習主講擔任嘉義基督教醫院之共同主持人戴德森醫療財團法人嘉義基督教醫院 
12108220207學術演講或教學講習主講協辦108學年度山海希望工程計畫-獎勵狀國立嘉義大學 
13108220207學術演講或教學講習主講擔任109學年第一學期"微生物於新興跨域食品生技加值技術之應用趨勢"授課師資國立嘉義大學 
14108220206學術演講或教學講習主講協助-山海希望工程計畫-教師講習活動嘉義縣黎明國小 
151081201911學術演講或教學講習主講協助-山海希望工程計畫-教師講習活動嘉義縣東石國小 
161081201910學術演講或教學講習主講協助-山海希望工程計畫-教師講習活動嘉義縣黎明國小 
17107220196學術演講或教學講習主講協助-山海希望工程計畫-教師講習活動嘉義縣安和國小 
181071201811學術演講或教學講習主講協助-山海希望工程計畫-教師講習活動嘉義縣東石國小 
191071201810學術演講或教學講習主講協助-山海希望工程計畫-教師講習活動嘉義縣黎明國小 
20106120181輔導106學年度第一學期未來與樂活產業學系碩士班研究生 李秋霖 學位考試委員 
211061201710輔導106學年度第一學期 化學工程學系系 博士班研究生 陳俊瑋 博士學位考試委員 
22105220176輔導105學年度第二學期未來與樂活產業學系未來學碩士班研究生 洪乙文 學位考試委員 
23105220175輔導2017國立嘉義大學微生物免疫與生物藥學系生命科學專題研究學生論文宣讀 
24105220175輔導2017國立嘉義大學微生物免疫與生物藥學系生命科學專題研究學生論文競賽暨生命科學產品研發成果競賽 
251051201611學術演講或教學講習主講協助-山海希望工程計畫-教師講習活動嘉義縣東石國小 
26104220163輔導105學年度大學個人申請入學招生委員會口試委員 
271041201512其他林芝嫻碩士口試委員 
281041201512其他楊淑棉碩士口試委員 
29103220154輔導擔任嘉義市第33屆國民中小學科學展覽會評審委員 
30102220146其他顧元傑碩士口試委員 
311021201312其他王尹辰碩士口試委員 
321021201312其他林永杰碩士口試委員