◎系所教育目標: 本系定位為發展農業生物科技,培養學生具生命科學和農業基礎知識,深入瞭解分子生物和生物技術的實際操作訓練,使學生成為學識與實務兼備的生物科技人才,著重於生物科技、作物科學、經濟動物、實驗動物和應用微生物的跨領域相關知識之整合,培養生物技術應用於農業之專業人才。 |
| ◎核心能力 | 關聯性 |
| 1.生物學相關專業知能 | 5 關聯性最強 |
| 2.生物技術相關專業知能 | 4 關聯性稍強 |
| 3.農業科學相關專業知能 | 5 關聯性最強 |
| 4.具備結合生物技術之理論與基因操作能力等農業科學技術實作能力 | 5 關聯性最強 |
| 5.動植物基因轉殖和細胞組織培養能力等農業科學技術實作能力 | 5 關聯性最強 |
| 6.跨領域生物技術、農業和生命科學知識、農業生態與環境保育能力 | 5 關聯性最強 |
| 7.在地文化關懷與全球意識 | 3 關聯性中等 |
| 8.人文和自我反思、道德素養能力 | 3 關聯性中等 |
◎本學科內容概述: 本學科為學士班課程。除探討遺傳學的基本概念與研究方法外,也探討細胞遺傳、分子遺傳、數量遺傳、族群遺傳、與演化遺傳,…等6個主要遺傳領域的現況與特點。透過本科目學習,將可擴展同學們的視野,並有助於遺傳理念的建構。其次,在探討演化遺傳時,可以拿突變來與演化的結果相對照,一方面可以瞭解基因突變的特點,也有益於對遺傳學的瞭解。 |
◎本學科教學內容大綱: 1.遺傳學的範圍。 2.孟德爾遺傳學。 3.生物統計分析。 4.細胞遺傳學。 5.分子遺傳學。 6.突變與遺傳學之關聯。 7.數量遺傳學。 8.族群遺傳學。 9.演化遺傳學。 |
◎本學科學習目標: 本系定位為發展農業生物科技,培養學生具生命科學和農業基礎知識,深入瞭解分子生物和生物技術的實際操作訓練,使學生成為學識與實務兼備的生物科技人才,著重於生物科技、作物科學、經濟動物、實驗動物和應用微生物的跨領域相關知識之整合,培養生物技術應用於農業之專業人才。 |
| ◎教學進度: |
| 週次 | 主題 | 教學內容 | 教學方法 |
01 02/25 | Introduction: The Science of Genetics | scope of Genetics
textbook
criteria of grading score
Three Great Milestones in Genetics | 問題教學法、講授、討論。 |
02 03/04 | Mendelism- The Basic Principles of Inheritance | Mendel’s Study of Heredity
Applications of Mendel’s Principles
Testing Genetic Hypotheses
Mendelian Principles in Human Genetic | 問題教學法、講授、討論。 |
03 03/11 | The Chromosomal Basis of Mendelism | Chromosomes
The Chromosome Theory of Heredity
Sex-Linked Genes in Humans
Sex Chromosomes and Sex Determination
Dosage Compensation of X-Linked Genes | 問題教學法、講授、討論。 |
04 03/18 | Variation in Chromosome Number and Structure | Cytological Techniques
Polyploidy
Aneuploidy
Rearrangements of Chromosome Structure | 問題教學法、講授、討論。 |
05 03/25 | Linkage, Crossing Over, and Chromosome Mapping in Eukaryotes | Linkage, Recombination, and Crossing Over
Chromosome Mapping
Cytogenetic Mapping
Linakge Analysis in Humans
Recombination and Evolution | 問題教學法、講授、討論。 |
06 04/01 | DNA and the Molecular Structure of Chromosomes | Functions of the Genetic Material
Proof That Genetic Information Is Stored in DNA
The Structures of DNA and RNA
Chromosome Structure in Prokaryotes and Viruses
Chromosome Structure in Eukaryotes | 問題教學法、講授、討論。 |
07 04/08 | Replication of DNA and Chromosomes | Basic Features of DNA Replication In Vivo
DNA Replication in Prokaryotes
Unique Aspects of Eukaryotic Chromosome Replication | 問題教學法、講授、討論。 |
08 04/15 | Mutation, DNA Repair, and Recombination | Transfer of Genetic Information: The Central Dogma
The Process of Gene Expression
Transcription in Prokaryotes
Transcription and RNA Processing in Eukaryotes
Interrupted Genes in Eukaryotes: Exons and Introns
Removal of Intron Sequences by RNA Splicing | 問題教學法、講授、討論。 |
09 04/22 | 期中考 | 期中考 | 問題教學法、講授、討論、期中考。 |
10 04/29 | Translation and the Genetic Code | Protein Structure
Protein Synthesis: Translation
The Genetic Code
Codon-tRNA Interactions | 問題教學法、講授、討論。 |
11 05/06 | Mutation, DNA Repair, and Recombination | Mutation: Source of the Genetic Variability Required for Evolution
The Molecular Basis of Mutation
Mutation: Basic Features of the Process
Mutation: Phenotypic Effects
Assigning Mutations to Genes by the Complementation Test
Screening Chemicals for Mutagenicity: The Ames Test
DNA Repair Mechanisms
Inherited Human Diseases with Defects in DNA Repair
DNA Recombination Mechanisms | 問題教學法、講授、討論。 |
12 05/13 | Genomics | Genomics: An Overview
Correlated Genetic, Cytological, and Physical Maps of Chromosomes
Map Position-Based Cloning of Genes
The Human Genome Project
RNA and Protein Assays of Genome Function
Comparative Genomics | 問題教學法、口頭報告、講授、討論。 |
13 05/20 | Transposable Genetic Elements | Transposable Elements: An Overview
Transposable Elements in Bacteria
Cut-and-Paste Transposons in Eukaryotes
Retroviruses and Retrotransposons
Transposable Elements in Humans
The Genetic and Evolutionary Significance of Transposable Elements | 問題教學法、口頭報告、講授、討論。 |
14 05/27 | The Genetic Control of Animal Development | A Genetic Perspective on Development
Maternal Gene Activity in Development
Zygotic Gene Activity in Development
Genetic Analysis of Development in Vertebrates | 問題教學法、口頭報告、講授、討論。 |
15 06/03 | Inheritance of Complex Traits | Complex Traits
Statistics of Quantitative Genetics
Analysis of Quantitative Traits
Correlations Between Relatives
Quantitative Genetics of Human Behavioral Traits | 問題教學法、口頭報告、講授、討論。 |
16 06/10 | Population Genetics | The Theory of Allele Frequencies
Natural Selection
Random Genetic Drift
Populations in Genetic Equilibrium | 問題教學法、口頭報告、講授、討論。 |
17 06/17 | Evolutionary Genetics | The Emergence of Evolutionary Theory
Genetic Variation in Natural Populations
Molecular Evolution
Speciation
Human Evolution | 問題教學法、口頭報告、講授、討論。 |
18 06/24 | 期末考 | 期末考 | 問題教學法、講授、討論。 |
◎課程要求: 使學生能瞭遺傳學之範圍、基因結構、運作、應用原理、與方法。
上課要專心。 |
◎成績考核 期中考33% : Test 2 期末考34% : Test 3 Test 1 33% 補充說明:三位授課老師共同決定本課程成績 |
◎參考書目與學習資源 1. Genetics,6th ed., Snustad and Simmons, Wiley Publishing.
2. Lehninger’s Principles of Biochemistry, 4th ed., D.L. Nelson and M.M. Cox, Worth Publishers.
3. Biochemistry, 6th ed., J.M. Berg, J.L. Tymoczko, and L. Stryer, W. H. Freeman and company. |
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